Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA060345-03
Application #
2101057
Study Section
AIDS and Related Research Study Section 5 (ARRE)
Project Start
1994-07-01
Project End
1997-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Emory University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
042250712
City
Atlanta
State
GA
Country
United States
Zip Code
30322
Harcourt, J L; Offermann, M K (2000) Interferon-alpha synergistically enhances induction of interleukin-6 by double stranded RNA in HeLa cells. Eur J Biochem 267:2768-77
Offermann, M K (1999) Consideration of host-viral interactions in the pathogenesis of Kaposi's sarcoma. J Acquir Immune Defic Syndr 21 Suppl 1:S58-65
Harcourt, B H; Sanchez, A; Offermann, M K (1999) Ebola virus selectively inhibits responses to interferons, but not to interleukin-1beta, in endothelial cells. J Virol 73:3491-6
Harcourt, B H; Rota, P A; Hummel, K B et al. (1999) Induction of intercellular adhesion molecule 1 gene expression by measles virus in human umbilical vein endothelial cells. J Med Virol 57:9-16
Kelly, G D; Morris, C B; Offermann, M K (1999) Lack of responsiveness of a nuclear factor-kappaB-regulated promoter to transactivation by human immunodeficiency virus 1 Tat in HeLa cells. Virology 263:128-38
Zimring, J C; Goodbourn, S; Offermann, M K (1998) Human herpesvirus 8 encodes an interferon regulatory factor (IRF) homolog that represses IRF-1-mediated transcription. J Virol 72:701-7
Kelly, G D; Ensoli, B; Gunthel, C J et al. (1998) Purified Tat induces inflammatory response genes in Kaposi's sarcoma cells. AIDS 12:1753-61
Offermann, M K (1996) HHV-8: a new herpesvirus associated with Kaposi's sarcoma. Trends Microbiol 4:383-6
Offermann, M K; Lin, J C; Mar, E C et al. (1996) Antioxidant-sensitive regulation of inflammatory-response genes in Kaposi's sarcoma cells. J Acquir Immune Defic Syndr Hum Retrovirol 13:1-11
Offermann, M K; Zimring, J; Mellits, K H et al. (1995) Activation of the double-stranded-RNA-activated protein kinase and induction of vascular cell adhesion molecule-1 by poly (I).poly (C) in endothelial cells. Eur J Biochem 232:28-36