Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA060643-03
Application #
2101388
Study Section
Special Emphasis Panel (SRC (50))
Project Start
1993-09-30
Project End
1997-09-29
Budget Start
1995-09-30
Budget End
1997-09-29
Support Year
3
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Fox Chase Cancer Center
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19111
Abdollahi, A; Godwin, A K; Miller, P D et al. (1997) Identification of a gene containing zinc-finger motifs based on lost expression in malignantly transformed rat ovarian surface epithelial cells. Cancer Res 57:2029-34
Dyck, H G; Hamilton, T C; Godwin, A K et al. (1996) Autonomy of the epithelial phenotype in human ovarian surface epithelium: changes with neoplastic progression and with a family history of ovarian cancer. Int J Cancer 69:429-36
Salazar, H; Godwin, A K; Daly, M B et al. (1996) Microscopic benign and invasive malignant neoplasms and a cancer-prone phenotype in prophylactic oophorectomies. J Natl Cancer Inst 88:1810-20
Rebbeck, T R; Godwin, A K; Buetow, K H (1996) Variability in loss of constitutional heterozygosity across loci and among individuals: association with candidate genes in ductal breast carcinoma. Mol Carcinog 17:117-25
Berman, D B; Costalas, J; Schultz, D C et al. (1996) A common mutation in BRCA2 that predisposes to a variety of cancers is found in both Jewish Ashkenazi and non-Jewish individuals. Cancer Res 56:3409-14
Schultz, D C; Vanderveer, L; Berman, D B et al. (1996) Identification of two candidate tumor suppressor genes on chromosome 17p13.3. Cancer Res 56:1997-2002
Berman, D B; Wagner-Costalas, J; Schultz, D C et al. (1996) Two distinct origins of a common BRCA1 mutation in breast-ovarian cancer families: a genetic study of 15 185delAG-mutation kindreds. Am J Hum Genet 58:1166-76
Godwin, A K; Miller, P D; Getts, L A et al. (1995) Retroviral-like sequences specifically expressed in the rat ovary detect genetic differences between normal and transformed rat ovarian surface epithelial cells. Endocrinology 136:4640-9
Schultz, D C; Vanderveer, L; Buetow, K H et al. (1995) Characterization of chromosome 9 in human ovarian neoplasia identifies frequent genetic imbalance on 9q and rare alterations involving 9p, including CDKN2. Cancer Res 55:2150-7
Auersperg, N; Maines-Bandiera, S; Booth, J H et al. (1995) Expression of two mucin antigens in cultured human ovarian surface epithelium: influence of a family history of ovarian cancer. Am J Obstet Gynecol 173:558-65

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