Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA060670-04
Application #
2101423
Study Section
Special Emphasis Panel (SRC (50))
Project Start
1993-08-01
Project End
1998-05-31
Budget Start
1996-06-01
Budget End
1998-05-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Dana-Farber Cancer Institute
Department
Type
DUNS #
149617367
City
Boston
State
MA
Country
United States
Zip Code
02215
Strobel, T; Tai, Y T; Korsmeyer, S et al. (1998) BAD partly reverses paclitaxel resistance in human ovarian cancer cells. Oncogene 17:2419-27
Tai, Y T; Lee, S; Niloff, E et al. (1998) BAX protein expression and clinical outcome in epithelial ovarian cancer. J Clin Oncol 16:2583-90
Strobel, T; Swanson, L; Korsmeyer, S et al. (1997) Radiation-induced apoptosis is not enhanced by expression of either p53 or BAX in SW626 ovarian cancer cells. Oncogene 14:2753-8
Strobel, T; Swanson, L; Cannistra, S A (1997) In vivo inhibition of CD44 limits intra-abdominal spread of a human ovarian cancer xenograft in nude mice: a novel role for CD44 in the process of peritoneal implantation. Cancer Res 57:1228-32
Ottensmeier, C; Swanson, L; Strobel, T et al. (1996) Absence of constitutive EGF receptor activation in ovarian cancer cell lines. Br J Cancer 74:446-52
Strobel, T; Swanson, L; Korsmeyer, S et al. (1996) BAX enhances paclitaxel-induced apoptosis through a p53-independent pathway. Proc Natl Acad Sci U S A 93:14094-9
Cannistra, S A; DeFranzo, B; Niloff, J et al. (1995) Functional heterogeneity of CD44 molecules in ovarian cancer cell lines. Clin Cancer Res 1:333-42
Cannistra, S A; Ottensmeier, C; Niloff, J et al. (1995) Expression and function of beta 1 and alpha v beta 3 integrins in ovarian cancer. Gynecol Oncol 58:216-25
Cannistra, S A; Abu-Jawdeh, G; Niloff, J et al. (1995) CD44 variant expression is a common feature of epithelial ovarian cancer: lack of association with standard prognostic factors. J Clin Oncol 13:1912-21
Cannistra, S A; Ottensmeier, C; Tidy, J et al. (1994) Vascular cell adhesion molecule-1 expressed by peritoneal mesothelium partly mediates the binding of activated human T lymphocytes. Exp Hematol 22:996-1002

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