Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA060867-04
Application #
2101643
Study Section
Pathology A Study Section (PTHA)
Project Start
1993-08-04
Project End
1998-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Vanderbilt University Medical Center
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37212

  Publications

McIntyre, J Oliver; Scherer, Randy L; Matrisian, Lynn M (2010) Near-infrared optical proteolytic beacons for in vivo imaging of matrix metalloproteinase activity. Methods Mol Biol 622:279-304
Uddin, Md Jashim; Crews, Brenda C; Blobaum, Anna L et al. (2010) Selective visualization of cyclooxygenase-2 in inflammation and cancer by targeted fluorescent imaging agents. Cancer Res 70:3618-27
VanSaun, Michael Nathan; Lee, In Kyu; Washington, Mary Kay et al. (2009) High fat diet induced hepatic steatosis establishes a permissive microenvironment for colorectal metastases and promotes primary dysplasia in a murine model. Am J Pathol 175:355-64
Sinnamon, Mark J; Carter, Kathy J; Fingleton, Barbara et al. (2008) Matrix metalloproteinase-9 contributes to intestinal tumourigenesis in the adenomatous polyposis coli multiple intestinal neoplasia mouse. Int J Exp Pathol 89:466-75
Scherer, Randy L; VanSaun, Michael N; McIntyre, J Oliver et al. (2008) Optical imaging of matrix metalloproteinase-7 activity in vivo using a proteolytic nanobeacon. Mol Imaging 7:118-31
Scherer, Randy L; McIntyre, J Oliver; Matrisian, Lynn M (2008) Imaging matrix metalloproteinases in cancer. Cancer Metastasis Rev 27:679-90
Sinnamon, Mark J; Carter, Kathy J; Sims, Lauren P et al. (2008) A protective role of mast cells in intestinal tumorigenesis. Carcinogenesis 29:880-6
Fingleton, Barbara; Powell, William C; Crawford, Howard C et al. (2007) A rat monoclonal antibody that recognizes pro- and active MMP-7 indicates polarized expression in vivo. Hybridoma (Larchmt) 26:22-7
Nicoud, Ian B; Jones, Christopher M; Pierce, Janene M et al. (2007) Warm hepatic ischemia-reperfusion promotes growth of colorectal carcinoma micrometastases in mouse liver via matrix metalloproteinase-9 induction. Cancer Res 67:2720-8
Fingleton, Barbara; Carter, Kathy J; Matrisian, Lynn M (2007) Loss of functional Fas ligand enhances intestinal tumorigenesis in the Min mouse model. Cancer Res 67:4800-6

Showing the most recent 10 out of 48 publications