Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA060914-02
Application #
2101687
Study Section
Bio-Organic and Natural Products Chemistry Study Section (BNP)
Project Start
1995-09-01
Project End
1998-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Ohio State University
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
098987217
City
Columbus
State
OH
Country
United States
Zip Code
43210

  Publications

Woo, S H; Sun, N J; Cassady, J M et al. (1999) Topoisomerase II inhibition by aporphine alkaloids. Biochem Pharmacol 57:1141-5
Huang, K C; Yamasaki, E F; Snapka, R M (1999) Maintenance of episomal SV40 genomes in GM637 human fibroblasts. Virology 262:457-69
Sun, N J; Woo, S H; Cassady, J M et al. (1998) DNA polymerase and topoisomerase II inhibitors from Psoralea corylifolia. J Nat Prod 61:362-6
Woo, S H; Reynolds, M C; Sun, N J et al. (1997) Inhibition of topoisomerase II by liriodenine. Biochem Pharmacol 54:467-73
Snapka, R M; Woo, S H; Blokhin, A V et al. (1996) Inhibition of topoisomerase II by ICRF-193, the meso isomer of 2,3-bis(2,6-dioxopiperazin-4-yl)butane. Critical dependence on 2,3-butanediyl linker absolute configuration. Biochem Pharmacol 52:543-9