Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA061335-03
Application #
2102075
Study Section
Special Emphasis Panel (SRC (54))
Project Start
1993-12-15
Project End
1997-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas Health Science Center San Antonio
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
800772162
City
San Antonio
State
TX
Country
United States
Zip Code
78229
Walter, C A; Intano, G W; McCarrey, J R et al. (1998) Mutation frequency declines during spermatogenesis in young mice but increases in old mice. Proc Natl Acad Sci U S A 95:10015-9
Zhang, L P; Stroud, J C; Walter, C A et al. (1998) A gene-specific promoter in transgenic mice directs testis-specific demethylation prior to transcriptional activation In vivo. Biol Reprod 59:284-92
Zhou, Z Q; Walter, C A (1998) Cloning and characterization of the promoter of baboon XRCC1, a gene involved in DNA strand-break repair. Somat Cell Mol Genet 24:23-39
Kamel, D; Mackey, Z B; Sjoblom, T et al. (1997) Role of deoxyribonucleic acid polymerase epsilon in spermatogenesis in mice. Biol Reprod 57:1367-74
Conrad, C C; Walter, C A; Richardson, A et al. (1997) Cadmium toxicity and distribution in metallothionein-I and -II deficient transgenic mice. J Toxicol Environ Health 52:527-43
Walter, C A; Grabowski, D T; Street, K A et al. (1997) Analysis and modulation of DNA repair in aging. Mech Ageing Dev 98:203-22
Mackey, Z B; Ramos, W; Levin, D S et al. (1997) An alternative splicing event which occurs in mouse pachytene spermatocytes generates a form of DNA ligase III with distinct biochemical properties that may function in meiotic recombination. Mol Cell Biol 17:989-98
Brookman, K W; Lamerdin, J E; Thelen, M P et al. (1996) ERCC4 (XPF) encodes a human nucleotide excision repair protein with eukaryotic recombination homologs. Mol Cell Biol 16:6553-62
Walter, C A; Trolian, D A; McFarland, M B et al. (1996) Xrcc-1 expression during male meiosis in the mouse. Biol Reprod 55:630-5
Zhou, Z Q; Walter, C A (1995) Expression of the DNA repair gene XRCC1 in baboon tissues. Mutat Res 348:111-6