Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA061344-04
Application #
2102085
Study Section
Special Emphasis Panel (SRC (56))
Project Start
1993-07-01
Project End
1997-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Georgetown University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
049515844
City
Washington
State
DC
Country
United States
Zip Code
20057

  Publications

Thompson, E W; Sung, V; Lavigne, M et al. (1999) LCC15-MB: a vimentin-positive human breast cancer cell line from a femoral bone metastasis. Clin Exp Metastasis 17:193-204
Gilles, C; Bassuk, J A; Pulyaeva, H et al. (1998) SPARC/osteonectin induces matrix metalloproteinase 2 activation in human breast cancer cell lines. Cancer Res 58:5529-36
Sung, V; Gilles, C; Murray, A et al. (1998) The LCC15-MB human breast cancer cell line expresses osteopontin and exhibits an invasive and metastatic phenotype. Exp Cell Res 241:273-84
Sung, V; Cattell, D A; Bueno, J M et al. (1997) Human breast cancer cell metastasis to long bone and soft organs of nude mice: a quantitative assay. Clin Exp Metastasis 15:173-83
Gilles, C; Polette, M; Seiki, M et al. (1997) Implication of collagen type I-induced membrane-type 1-matrix metalloproteinase expression and matrix metalloproteinase-2 activation in the metastatic progression of breast carcinoma. Lab Invest 76:651-60
Yu, M; Sato, H; Seiki, M et al. (1997) Calcium influx inhibits MT1-MMP processing and blocks MMP-2 activation. FEBS Lett 412:568-72
Yu, M; Bowden, E T; Sitlani, J et al. (1997) Tyrosine phosphorylation mediates ConA-induced membrane type 1-matrix metalloproteinase expression and matrix metalloproteinase-2 activation in MDA-MB-231 human breast carcinoma cells. Cancer Res 57:5028-32
Gilles, C; Polette, M; Birembaut, P et al. (1997) Expression of c-ets-1 mRNA is associated with an invasive, EMT-derived phenotype in breast carcinoma cell lines. Clin Exp Metastasis 15:519-26
Pulyaeva, H; Bueno, J; Polette, M et al. (1997) MT1-MMP correlates with MMP-2 activation potential seen after epithelial to mesenchymal transition in human breast carcinoma cells. Clin Exp Metastasis 15:111-20
Yu, M; Sato, H; Seiki, M et al. (1995) Complex regulation of membrane-type matrix metalloproteinase expression and matrix metalloproteinase-2 activation by concanavalin A in MDA-MB-231 human breast cancer cells. Cancer Res 55:3272-7

Showing the most recent 10 out of 11 publications