Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA061593-04
Application #
2102327
Study Section
Special Emphasis Panel (SRC (57))
Project Start
1993-09-30
Project End
1997-07-31
Budget Start
1996-08-13
Budget End
1997-07-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Nebraska Medical Center
Department
Pathology
Type
Schools of Medicine
DUNS #
City
Omaha
State
NE
Country
United States
Zip Code
68198
Fernandes, Margret S; Reddy, Mamatha M; Croteau, Nicole J et al. (2010) Novel oncogenic mutations of CBL in human acute myeloid leukemia that activate growth and survival pathways depend on increased metabolism. J Biol Chem 285:32596-605
Talmadge, J E; Singh, R; Ageitos, A et al. (2001) Potential for cytokine and product manipulation to improve the results of autologous stem cell transplantation for rheumatoid arthritis. J Rheumatol Suppl 64:32-8
Ino, K; Ageitos, A G; Singh, R K et al. (2001) Activation-induced T cell apoptosis by monocytes from stem cell products. Int Immunopharmacol 1:1307-19
Singh, R K; Varney, M L; Ino, K et al. (2000) Immune dysfunction despite high levels of immunoregulatory cytokine gene expression in autologous peripheral blood stem cell transplanted non-Hodgkin's lymphoma patients. Exp Hematol 28:499-507
Bierman, P J; Abe, F; Buyukberber, S et al. (2000) Partial review of immunotherapeutic pharmacology in stem cell transplantation. In Vivo 14:221-36
Talmadge, J E; Singh, R; Ino, K et al. (2000) Mechanisms of immune dysfunction in stem cell transplantation. Int J Immunopharmacol 22:1041-56
Singh, R K; Varney, M L; Buyukberber, S et al. (1999) Fas-FasL-mediated CD4+ T-cell apoptosis following stem cell transplantation. Cancer Res 59:3107-11
Singh, R K; Ino, K; Varney, M L et al. (1999) Immunoregulatory cytokines in bone marrow and peripheral blood stem cell products. Bone Marrow Transplant 23:53-62
Varney, M L; Ino, K; Ageitos, A G et al. (1999) Expression of interleukin-10 in isolated CD8+ T cells and monocytes from growth factor-mobilized peripheral blood stem cell products: a mechanism of immune dysfunction. J Interferon Cytokine Res 19:351-60
Ageitos, A G; Varney, M L; Bierman, P J et al. (1999) Comparison of monocyte-dependent T cell inhibitory activity in GM-CSF vs G-CSF mobilized PSC products. Bone Marrow Transplant 23:63-9

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