Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA062042-03
Application #
2103009
Study Section
Pathobiochemistry Study Section (PBC)
Project Start
1994-09-16
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Sanford-Burnham Medical Research Institute
Department
Type
DUNS #
009214214
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Ruoslahti, E (1999) Fibronectin and its integrin receptors in cancer. Adv Cancer Res 76:1-20
MacKenna, D A; Dolfi, F; Vuori, K et al. (1998) Extracellular signal-regulated kinase and c-Jun NH2-terminal kinase activation by mechanical stretch is integrin-dependent and matrix-specific in rat cardiac fibroblasts. J Clin Invest 101:301-10
Bourdoulous, S; Orend, G; MacKenna, D A et al. (1998) Fibronectin matrix regulates activation of RHO and CDC42 GTPases and cell cycle progression. J Cell Biol 143:267-76
Arap, W; Pasqualini, R; Ruoslahti, E (1998) Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model. Science 279:377-80
Frisch, S M; Ruoslahti, E (1997) Integrins and anoikis. Curr Opin Cell Biol 9:701-6
Ruoslahti, E (1997) Integrins as signaling molecules and targets for tumor therapy. Kidney Int 51:1413-7
Pasqualini, R; Bourdoulous, S; Koivunen, E et al. (1996) A polymeric form of fibronectin has antimetastatic effects against multiple tumor types. Nat Med 2:1197-203
Ruoslahti, E (1996) Integrin signaling and matrix assembly. Tumour Biol 17:117-24
Zhang, Z; Vuori, K; Wang, H et al. (1996) Integrin activation by R-ras. Cell 85:61-9
Pasqualini, R; Koivunen, E; Ruoslahti, E (1996) Peptides in cell adhesion: powerful tools for the study of integrin-ligand interactions. Braz J Med Biol Res 29:1151-8

Showing the most recent 10 out of 13 publications