Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA063335-03
Application #
2105117
Study Section
Metabolic Pathology Study Section (MEP)
Project Start
1994-06-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Maryland Baltimore
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
003255213
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Fontana, J A; Dawson, M I; Leid, M et al. (2000) Identification of a unique binding protein specific for a novel retinoid inducing cellular apoptosis. Int J Cancer 86:474-9
Farhana, L; Boyanapalli, M; Tschang, S H et al. (2000) Okadaic acid-mediated induction of the c-fos gene in estrogen receptor-negative human breast carcinoma cells utilized, in part, posttranscriptional mechanisms involving adenosine-uridine-rich elements. Cell Growth Differ 11:541-50
Rishi, A K; Sun, R J; Gao, Y et al. (1999) Post-transcriptional regulation of the DNA damage-inducible gadd45 gene in human breast carcinoma cells exposed to a novel retinoid CD437. Nucleic Acids Res 27:3111-9
Zhang, Y; Huang, Y; Rishi, A K et al. (1999) Activation of the p38 and JNK/SAPK mitogen-activated protein kinase pathways during apoptosis is mediated by a novel retinoid. Exp Cell Res 247:233-40
Shao, Z M; Alpaugh, M L; Fontana, J A et al. (1998) Genistein inhibits proliferation similarly in estrogen receptor-positive and negative human breast carcinoma cell lines characterized by P21WAF1/CIP1 induction, G2/M arrest, and apoptosis. J Cell Biochem 69:44-54
Fontana, J A; Sun, R J; Rishi, A K et al. (1998) Overexpression of bcl-2 or bcl-XL fails to inhibit apoptosis mediated by a novel retinoid. Oncol Res 10:313-24
Hsu, C K; Rishi, A K; Li, X S et al. (1997) Bcl-X(L) expression and its downregulation by a novel retinoid in breast carcinoma cells. Exp Cell Res 232:17-24
Hsu, C A; Rishi, A K; Su-Li, X et al. (1997) Retinoid induced apoptosis in leukemia cells through a retinoic acid nuclear receptor-independent pathway. Blood 89:4470-9
Rishi, A K; Hsu, C K; Li, X S et al. (1997) Transcriptional repression of the cyclin-dependent kinase inhibitor p21WAF1/CIP1 gene mediated by cis elements present in the 3'-untranslated region. Cancer Res 57:5129-36
Rishi, A K; Gerald, T M; Shao, Z M et al. (1996) Regulation of the human retinoic acid receptor alpha gene in the estrogen receptor negative human breast carcinoma cell lines SKBR-3 and MDA-MB-435. Cancer Res 56:5246-52

Showing the most recent 10 out of 19 publications