Type IV Collagen in Melanoma Cell Invasion & Metastasis

McCarthy, James B.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: Research Project (R01)
• Project #: 5R01CA063671-02
• Application #: 2105669
• Study Section: Pathology B Study Section (PTHB)
• Project Start: 1995-07-01
• Project End: 2000-04-30
• Budget Start: 1996-05-01
• Budget End: 1997-04-30
• Support Year: 2
• Fiscal Year: 1996

Institution

• Name: University of Minnesota Twin Cities
• Department: Pathology
• Type: Schools of Medicine
• DUNS #: 168559177
• City: Minneapolis
• State: MN
• Country: United States
• Zip Code: 55455

Publications

Yu, Y C; Pakalns, T; Dori, Y et al. (1997) Construction of biologically active protein molecular architecture using self-assembling peptide-amphiphiles. Methods Enzymol 289:571-87

Li, C; McCarthy, J B; Furcht, L T et al. (1997) An all-D amino acid peptide model of alpha1(IV)531-543 from type IV collagen binds the alpha3beta1 integrin and mediates tumor cell adhesion, spreading, and motility. Biochemistry 36:15404-10

Lauer, J L; Furcht, L T; Fields, G B (1997) Inhibition of melanoma cell binding to type IV collagen by analogs of cell adhesion regulator. J Med Chem 40:3077-84

Grab, B; Miles, A J; Furcht, L T et al. (1996) Promotion of fibroblast adhesion by triple-helical peptide models of type I collagen-derived sequences. J Biol Chem 271:12234-40