Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA064118-02
Application #
2106389
Study Section
Pathology B Study Section (PTHB)
Project Start
1995-04-03
Project End
1999-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Vanderbilt University Medical Center
Department
Biochemistry
Type
Schools of Medicine
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37212
Kim, Sungeun; Denny, Christopher T; Wisdom, Ron (2006) Cooperative DNA binding with AP-1 proteins is required for transformation by EWS-Ets fusion proteins. Mol Cell Biol 26:2467-78
Sprowles, Amy; Robinson, Dan; Wu, Yi-Mi et al. (2005) c-Jun controls the efficiency of MAP kinase signaling by transcriptional repression of MAP kinase phosphatases. Exp Cell Res 308:459-68
Wisdom, Ron; Huynh, Lyanne; Hsia, Datsun et al. (2005) RAS and TGF-beta exert antagonistic effects on extracellular matrix gene expression and fibroblast transformation. Oncogene 24:7043-54
Sprowles, Amy; Wisdom, Ron (2003) Oncogenic effect of delta deletion in v-Jun does not result from uncoupling Jun from JNK signaling. Oncogene 22:498-506
Wisdom, R; Johnson, R S; Moore, C (1999) c-Jun regulates cell cycle progression and apoptosis by distinct mechanisms. EMBO J 18:188-97
Qu, S; Tucker, S C; Zhao, Q et al. (1999) Physical and genetic interactions between Alx4 and Cart1. Development 126:359-69
Tucker, S C; Wisdom, R (1999) Site-specific heterodimerization by paired class homeodomain proteins mediates selective transcriptional responses. J Biol Chem 274:32325-32
Qu, S; Tucker, S C; Ehrlich, J S et al. (1998) Mutations in mouse Aristaless-like4 cause Strong's luxoid polydactyly. Development 125:2711-21
Skinner, M; Qu, S; Moore, C et al. (1997) Transcriptional activation and transformation by FosB protein require phosphorylation of the carboxyl-terminal activation domain. Mol Cell Biol 17:2372-80
Qu, S; Li, L; Wisdom, R (1997) Alx-4: cDNA cloning and characterization of a novel paired-type homeodomain protein. Gene 203:217-23

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