Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
1R01CA065647-01A1
Application #
2108706
Study Section
Biochemical Endocrinology Study Section (BCE)
Project Start
1996-04-01
Project End
1999-11-30
Budget Start
1996-04-01
Budget End
1996-11-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Beth Israel Deaconess Medical Center
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02215
Wang, Hongyun; Leav, Irwin; Ibaragi, Soichiro et al. (2008) SOX9 is expressed in human fetal prostate epithelium and enhances prostate cancer invasion. Cancer Res 68:1625-30
Wang, Hongyun; McKnight, Nicole C; Zhang, Tao et al. (2007) SOX9 is expressed in normal prostate basal cells and regulates androgen receptor expression in prostate cancer cells. Cancer Res 67:528-36
Yuan, Xin; Li, Tong; Wang, Hongyun et al. (2006) Androgen receptor remains critical for cell-cycle progression in androgen-independent CWR22 prostate cancer cells. Am J Pathol 169:682-96
Fu, Maofu; Rao, Mahadev; Wang, Chenguang et al. (2003) Acetylation of androgen receptor enhances coactivator binding and promotes prostate cancer cell growth. Mol Cell Biol 23:8563-75
Masiello, David; Cheng, Shinta; Bubley, Glenn J et al. (2002) Bicalutamide functions as an androgen receptor antagonist by assembly of a transcriptionally inactive receptor. J Biol Chem 277:26321-6
Cheng, Shinta; Brzostek, Sabrina; Lee, Suzanne R et al. (2002) Inhibition of the dihydrotestosterone-activated androgen receptor by nuclear receptor corepressor. Mol Endocrinol 16:1492-501
Balk, Steven P (2002) Androgen receptor as a target in androgen-independent prostate cancer. Urology 60:132-8; discussion 138-9
Yuan, X; Lu, M L; Li, T et al. (2001) SRY interacts with and negatively regulates androgen receptor transcriptional activity. J Biol Chem 276:46647-54
Stanbrough, M; Leav, I; Kwan, P W et al. (2001) Prostatic intraepithelial neoplasia in mice expressing an androgen receptor transgene in prostate epithelium. Proc Natl Acad Sci U S A 98:10823-8
Taplin, M E; Bubley, G J; Ko, Y J et al. (1999) Selection for androgen receptor mutations in prostate cancers treated with androgen antagonist. Cancer Res 59:2511-5

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