Phase I Trial of Hsvtk Gene Therapy for CNS Tumors

Alavi, Jane B.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: Research Project (R01)
• Project #: 5R01CA067790-02
• Application #: 2008899
• Study Section: Special Emphasis Panel (SRC (14))
• Project Start: 1995-08-30
• Project End: 1998-07-31
• Budget Start: 1996-08-01
• Budget End: 1997-07-31
• Support Year: 2
• Fiscal Year: 1996

Institution

• Name: University of Pennsylvania
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• DUNS #: 042250712
• City: Philadelphia
• State: PA
• Country: United States
• Zip Code: 19104

Publications

Hustinx, R; Shiue, C Y; Alavi, A et al. (2001) Imaging in vivo herpes simplex virus thymidine kinase gene transfer to tumour-bearing rodents using positron emission tomography and. Eur J Nucl Med 28:5-12

Shiue, G G; Shiue, C Y; Lee, R L et al. (2001) A simplified one-pot synthesis of 9-[(3-[18F]fluoro-1-hydroxy-2-propoxy)methyl]guanine([18F]FHPG) and 9-(4-[18F]fluoro-3-hydroxymethylbutyl)guanine ([18F]FHBG) for gene therapy. Nucl Med Biol 28:875-83

Hustinx, R; Eck, S L; Alavi, A (1999) Potential applications of PET imaging in developing novel cancer therapies. J Nucl Med 40:995-1002