Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA067818-02
Application #
2111604
Study Section
Experimental Therapeutics Subcommittee 1 (ET)
Project Start
1995-09-30
Project End
1999-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Mayo Clinic, Rochester
Department
Type
DUNS #
City
Rochester
State
MN
Country
United States
Zip Code
55905
Bible, K C; Boerner, S A; Kirkland, K et al. (2000) Characterization of an ovarian carcinoma cell line resistant to cisplatin and flavopiridol. Clin Cancer Res 6:661-70
Budihardjo, I I; Boerner, S A; Eckdahl, S et al. (2000) Effect of 6-aminonicotinamide and other protein synthesis inhibitors on formation of platinum-DNA adducts and cisplatin sensitivity. Mol Pharmacol 57:529-38
Kaufmann, S H; Earnshaw, W C (2000) Induction of apoptosis by cancer chemotherapy. Exp Cell Res 256:42-9
Walker, D L; Reid, J M; Svingen, P A et al. (1999) Murine pharmacokinetics of 6-aminonicotinamide (NSC 21206), a novel biochemical modulating agent. Biochem Pharmacol 58:1057-66
Bible, K C; Boerner, S A; Kaufmann, S H (1999) A one-step method for protein estimation in biological samples: nitration of tyrosine in nitric acid. Anal Biochem 267:217-21
Budihardjo, I I; Walker, D L; Svingen, P A et al. (1998) 6-Aminonicotinamide sensitizes human tumor cell lines to cisplatin. Clin Cancer Res 4:117-30