Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
1R01CA068136-01A1
Application #
2111999
Study Section
Chemical Pathology Study Section (CPA)
Project Start
1996-05-25
Project End
1999-02-28
Budget Start
1996-05-25
Budget End
1997-02-28
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Weill Medical College of Cornell University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
201373169
City
New York
State
NY
Country
United States
Zip Code
10065
Subbaramaiah, K; Altorki, N; Chung, W J et al. (1999) Inhibition of cyclooxygenase-2 gene expression by p53. J Biol Chem 274:10911-5
Howe, L R; Subbaramaiah, K; Chung, W J et al. (1999) Transcriptional activation of cyclooxygenase-2 in Wnt-1-transformed mouse mammary epithelial cells. Cancer Res 59:1572-7
Subbaramaiah, K; Michaluart, P; Chung, W J et al. (1999) Resveratrol inhibits cyclooxygenase-2 transcription in human mammary epithelial cells. Ann N Y Acad Sci 889:214-23
Michaluart, P; Masferrer, J L; Carothers, A M et al. (1999) Inhibitory effects of caffeic acid phenethyl ester on the activity and expression of cyclooxygenase-2 in human oral epithelial cells and in a rat model of inflammation. Cancer Res 59:2347-52
Subbaramaiah, K; Chung, W J; Dannenberg, A J (1998) Ceramide regulates the transcription of cyclooxygenase-2. Evidence for involvement of extracellular signal-regulated kinase/c-Jun N-terminal kinase and p38 mitogen-activated protein kinase pathways. J Biol Chem 273:32943-9
Subbaramaiah, K; Chung, W J; Michaluart, P et al. (1998) Resveratrol inhibits cyclooxygenase-2 transcription and activity in phorbol ester-treated human mammary epithelial cells. J Biol Chem 273:21875-82
Subbaramaiah, K; Zakim, D; Weksler, B B et al. (1997) Inhibition of cyclooxygenase: a novel approach to cancer prevention. Proc Soc Exp Biol Med 216:201-10
Subbaramaiah, K; Telang, N; Bansal, M B et al. (1997) Cyclooxygenase-2 gene expression is upregulated in transformed mammary epithelial cells. Ann N Y Acad Sci 833:179-85
Kelley, D J; Mestre, J R; Subbaramaiah, K et al. (1997) Benzo[a]pyrene up-regulates cyclooxygenase-2 gene expression in oral epithelial cells. Carcinogenesis 18:795-9
Mestre, J R; Subbaramaiah, K; Sacks, P G et al. (1997) Phorbol ester-mediated induction of cyclooxygenase-2 gene expression is inhibited by retinoids. Ann N Y Acad Sci 833:173-8

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