Polynucleotide Vaccines for Colon Cancer and Melanoma

Conry, Robert M.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: Research Project (R01)
• Project #: 5R01CA068256-02
• Application #: 2112158
• Study Section: Experimental Therapeutics Subcommittee 1 (ET)
• Project Start: 1995-08-01
• Project End: 1999-05-31
• Budget Start: 1996-06-01
• Budget End: 1997-05-31
• Support Year: 2
• Fiscal Year: 1996

Institution

• Name: University of Alabama Birmingham
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• DUNS #: 004514360
• City: Birmingham
• State: AL
• Country: United States
• Zip Code: 35294

Publications

Triozzi, Pierre L; Aldrich, Wayne; Allen, Karen O et al. (2005) Phase I study of a plasmid DNA vaccine encoding MART-1 in patients with resected melanoma at risk for relapse. J Immunother 28:382-8

Conry, Robert M; Curiel, David T; Strong, Theresa V et al. (2002) Safety and immunogenicity of a DNA vaccine encoding carcinoembryonic antigen and hepatitis B surface antigen in colorectal carcinoma patients. Clin Cancer Res 8:2782-7

Lee, S W; Li, H; Strong, T V et al. (2000) Development of a polynucleotide vaccine from melanoma antigen recognized by T cells-1 and recombinant protein from melanoma antigen recognized by T cells-1 for melanoma vaccine clinical trials. J Immunother 23:379-86

Conry, R M; White, S A; Fultz, P N et al. (1998) Polynucleotide immunization of nonhuman primates against carcinoembryonic antigen. Clin Cancer Res 4:2903-12

Strong, T V; Hampton, T A; Louro, I et al. (1997) Incorporation of beta-globin untranslated regions into a Sindbis virus vector for augmentation of heterologous mRNA expression. Gene Ther 4:624-7

Conry, R M; LoBuglio, A F; Curiel, D T (1996) Polynucleotide-mediated immunization therapy of cancer. Semin Oncol 23:135-47