Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA068535-02
Application #
2112526
Study Section
Epidemiology and Disease Control Subcommittee 2 (EDC)
Project Start
1995-07-01
Project End
1999-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Mayo Clinic, Rochester
Department
Type
DUNS #
City
Rochester
State
MN
Country
United States
Zip Code
55905
Boardman, Lisa A; Lanier, Anne P; French, Amy J et al. (2007) Frequency of defective DNA mismatch repair in colorectal cancer among the Alaska Native people. Cancer Epidemiol Biomarkers Prev 16:2344-50
Wang, Liang; Cunningham, Julie M; Winters, Jennifer L et al. (2003) BRAF mutations in colon cancer are not likely attributable to defective DNA mismatch repair. Cancer Res 63:5209-12
Lindor, Noralane M; Burgart, Lawrence J; Leontovich, Olga et al. (2002) Immunohistochemistry versus microsatellite instability testing in phenotyping colorectal tumors. J Clin Oncol 20:1043-8
Cunningham, J M; Kim, C Y; Christensen, E R et al. (2001) The frequency of hereditary defective mismatch repair in a prospective series of unselected colorectal carcinomas. Am J Hum Genet 69:780-90
Boardman, L A; Schmidt, S; Lindor, N M et al. (2001) A search for germline APC mutations in early onset colorectal cancer or familial colorectal cancer with normal DNA mismatch repair. Genes Chromosomes Cancer 30:181-6
Karnes Jr, W E (2000) Implications of low COX-2 expression in colorectal neoplasms with defective DNA mismatch repair. J Cell Biochem Suppl 34:23-7
Parc, Y R; Halling, K C; Wang, L et al. (2000) HMSH6 alterations in patients with microsatellite instability-low colorectal cancer. Cancer Res 60:2225-31
Parc, Y R; Halling, K C; Burgart, L J et al. (2000) Microsatellite instability and hMLH1/hMSH2 expression in young endometrial carcinoma patients: associations with family history and histopathology. Int J Cancer 86:60-6
Yang, P; Cunningham, J M; Halling, K C et al. (2000) Higher risk of mismatch repair-deficient colorectal cancer in alpha(1)-antitrypsin deficiency carriers and cigarette smokers. Mol Genet Metab 71:639-45
Thibodeau, S N; French, A J; Cunningham, J M et al. (1998) Microsatellite instability in colorectal cancer: different mutator phenotypes and the principal involvement of hMLH1. Cancer Res 58:1713-8

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