Structure and Function of Tap

Androlewicz, Matthew J.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: Research Project (R01)
• Project #: 1R01CA069115-01
• Application #: 2113188
• Study Section: Experimental Immunology Study Section (EI)
• Project Start: 1996-05-01
• Project End: 1999-04-30
• Budget Start: 1996-05-01
• Budget End: 1997-04-30
• Support Year: 1
• Fiscal Year: 1996

Institution

• Name: University of South Florida
• Department: Biochemistry
• Type: Schools of Medicine
• City: Tampa
• State: FL
• Country: United States
• Zip Code: 33612

Publications

Androlewicz, M J (2001) Peptide generation in the major histocompatibility complex class I antigen processing and presentation pathway. Curr Opin Hematol 8:12-6

Chen, D; Androlewicz, M J (2001) Heat shock protein 70 moderately enhances peptide binding and transport by the transporter associated with antigen processing. Immunol Lett 75:143-8

Wang, Y; Androlewicz, M J (2000) Oligosaccharide trimming plays a role in the endoplasmic reticulum-associated degradation of tyrosinase. Biochem Biophys Res Commun 271:22-7

Androlewicz, M J (1999) The role of tapasin in MHC class I antigen assembly. Immunol Res 20:79-88

Wang, Y; Chen, D; Androlewicz, M J (1999) The role of endoplasmic reticulum-associated protein degradation in MHC class I antigen processing. Immunol Rev 172:67-72

Lacaille, V G; Androlewicz, M J (1998) Herpes simplex virus inhibitor ICP47 destabilizes the transporter associated with antigen processing (TAP) heterodimer. J Biol Chem 273:17386-90

Stephens, D B; Androlewicz, M J (1997) Reconstitution of peptide-binding activity by TAP in proteoliposomes. FEBS Lett 416:353-8