Control of C Myc Transcription in High Grade Lymphomas

Boxer, Linda M.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: Research Project (R01)
• Project #: 1R01CA069322-01
• Application #: 2113405
• Study Section: Pathology B Study Section (PTHB)
• Project Start: 1996-04-15
• Project End: 2001-01-31
• Budget Start: 1996-04-15
• Budget End: 1997-01-31
• Support Year: 1
• Fiscal Year: 1996

Institution

• Name: Stanford University
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• DUNS #: 800771545
• City: Stanford
• State: CA
• Country: United States
• Zip Code: 94305

Publications

Hu, H-M; Kanda, K; Zhang, L et al. (2007) Activation of the c-myc p1 promoter in Burkitt's lymphoma by the hs3 immunoglobulin heavy-chain gene enhancer. Leukemia 21:747-53

Wang, Jinghong; Boxer, Linda M (2005) Regulatory elements in the immunoglobulin heavy chain gene 3'-enhancers induce c-myc deregulation and lymphomagenesis in murine B cells. J Biol Chem 280:12766-73

Hu, Hsien-Ming; Arcinas, Magdalena; Boxer, Linda M (2002) A Myc-associated zinc finger protein-related factor binding site is required for the deregulation of c-myc expression by the immunoglobulin heavy chain gene enhancers in Burkitt's lymphoma. J Biol Chem 277:9819-24

Boxer, L M; Dang, C V (2001) Translocations involving c-myc and c-myc function. Oncogene 20:5595-610

Arcinas, M; Heckman, C A; Mehew, J W et al. (2001) Molecular mechanisms of transcriptional control of bcl-2 and c-myc in follicular and transformed lymphoma. Cancer Res 61:5202-6

Kanda, K; Hu, H M; Zhang, L et al. (2000) NF-kappa B activity is required for the deregulation of c-myc expression by the immunoglobulin heavy chain enhancer. J Biol Chem 275:32338-46

Liu, J; Li, C; Ahlborn, T E et al. (1999) The expression of p53 tumor suppressor gene in breast cancer cells is down-regulated by cytokine oncostatin M. Cell Growth Differ 10:677-83