Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA069959-07
Application #
2113920
Study Section
Experimental Immunology Study Section (EI)
Project Start
1989-09-30
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Florida
Department
Microbiology/Immun/Virology
Type
Schools of Earth Sciences/Natur
DUNS #
073130411
City
Gainesville
State
FL
Country
United States
Zip Code
32611

  Publications

Soos, Jeanne M; Stuve, Olaf; Youssef, Sawsan et al. (2002) Cutting edge: oral type I IFN-tau promotes a Th2 bias and enhances suppression of autoimmune encephalomyelitis by oral glatiramer acetate. J Immunol 169:2231-5
Torres, Barbara A; Perrin, George Q; Mujtaba, Mustafa G et al. (2002) Superantigen enhancement of specific immunity: antibody production and signaling pathways. J Immunol 169:2907-14
Soos, Jeanne M; Mujtaba, Mustafa G; Schiffenbauer, Joel et al. (2002) Intramolecular epitope spreading induced by staphylococcal enterotoxin superantigen reactivation of experimental allergic encephalomyelitis. J Neuroimmunol 123:30-4
Tanabe, T; Kominsky, S L; Subramaniam, P S et al. (2000) Inhibition of the glioblastoma cell cycle by type I IFNs occurs at both the G1 and S phases and correlates with the upregulation of p21(WAF1/CIP1). J Neurooncol 48:225-32
Subramaniam, P S; Larkin 3rd, J; Mujtaba, M G et al. (2000) The COOH-terminal nuclear localization sequence of interferon gamma regulates STAT1 alpha nuclear translocation at an intracellular site. J Cell Sci 113 ( Pt 15):2771-81
Mujtaba, M G; Villarete, L; Johnson, H M (1999) IFN-tau inhibits IgE production in a murine model of allergy and in an IgE-producing human myeloma cell line. J Allergy Clin Immunol 104:1037-44
Johnson, T M; Holaday, S K; Sun, Y et al. (1999) Expression, purification, and characterization of interferon-tau produced in Pichia pastoris grown in a minimal medium. J Interferon Cytokine Res 19:631-6
Radhakrishnan, R; Walter, L J; Subramaniam, P S et al. (1999) Crystal structure of ovine interferon-tau at 2.1 A resolution. J Mol Biol 286:151-62
Mujtaba, M G; Streit, W J; Johnson, H M (1998) IFN-tau suppresses both the autoreactive humoral and cellular immune responses and induces stable remission in mice with chronic experimental allergic encephalomyelitis. Cell Immunol 186:94-102
Subramaniam, P S; Cruz, P E; Hobeika, A C et al. (1998) Type I interferon induction of the Cdk-inhibitor p21WAF1 is accompanied by ordered G1 arrest, differentiation and apoptosis of the Daudi B-cell line. Oncogene 16:1885-90

Showing the most recent 10 out of 16 publications