Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA070036-02
Application #
2113991
Study Section
AIDS and Related Research Study Section 3 (ARRC)
Project Start
1995-09-30
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Yale University
Department
Pediatrics
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Miller, George; El-Guindy, Ayman; Countryman, Jill et al. (2007) Lytic cycle switches of oncogenic human gammaherpesviruses. Adv Cancer Res 97:81-109
Ye, Jianjiang; Shedd, Duane; Miller, George (2005) An Sp1 response element in the Kaposi's sarcoma-associated herpesvirus open reading frame 50 promoter mediates lytic cycle induction by butyrate. J Virol 79:1397-408
Chang, Pey-Jium; Shedd, Duane; Miller, George (2005) Two subclasses of Kaposi's sarcoma-associated herpesvirus lytic cycle promoters distinguished by open reading frame 50 mutant proteins that are deficient in binding to DNA. J Virol 79:8750-63
Chen, Lee-Wen; Chang, Pey-Jium; Delecluse, Henri-Jacques et al. (2005) Marked variation in response of consensus binding elements for the Rta protein of Epstein-Barr virus. J Virol 79:9635-50
Chang, Pey-Jium; Miller, George (2004) Autoregulation of DNA binding and protein stability of Kaposi's sarcoma-associated herpesvirus ORF50 protein. J Virol 78:10657-73
Dela Cruz, Charles S; Lee, Yoomi; Viswanathan, Srinivas R et al. (2004) N-linked glycosylation is required for optimal function of Kaposi's sarcoma herpesvirus-encoded, but not cellular, interleukin 6. J Exp Med 199:503-14
Chang, Pey-Jium; Shedd, Duane; Gradoville, Lyn et al. (2002) Open reading frame 50 protein of Kaposi's sarcoma-associated herpesvirus directly activates the viral PAN and K12 genes by binding to related response elements. J Virol 76:3168-78
Almuneef, M; Nimjee, S; Khoshnood, K et al. (2001) Prevalence of antibodies to human herpesvirus 8 (HHV-8) in Saudi Arabian patients with and without renal failure. Transplantation 71:1120-4
Gradoville, L; Gerlach, J; Grogan, E et al. (2000) Kaposi's sarcoma-associated herpesvirus open reading frame 50/Rta protein activates the entire viral lytic cycle in the HH-B2 primary effusion lymphoma cell line. J Virol 74:6207-12
Cinquina, C C; Grogan, E; Sun, R et al. (2000) Dihydrofolate reductase from Kaposi's sarcoma-associated herpesvirus. Virology 268:201-17

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