Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
1R01CA070274-01
Application #
2114194
Study Section
Molecular and Cellular Biophysics Study Section (BBCA)
Project Start
1996-04-05
Project End
1999-03-31
Budget Start
1996-04-05
Budget End
1997-03-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Nevada Reno
Department
Biochemistry
Type
Schools of Medicine
DUNS #
146515460
City
Reno
State
NV
Country
United States
Zip Code
89557
Sahu, Geetaram; Wang, Difei; Chen, Claudia B et al. (2010) p53 binding to nucleosomal DNA depends on the rotational positioning of DNA response element. J Biol Chem 285:1321-32
Balagurumoorthy, P; Lindsay, Stuart M; Harrington, Rodney E (2002) Atomic force microscopy reveals kinks in the p53 response element DNA. Biophys Chem 101-102:611-23
Zhou, H; Zhang, Y; Ou-Yang, Z et al. (2001) Conformation and rigidity of DNA microcircles containing waf1 response element for p53 regulatory protein. J Mol Biol 306:227-38
Feng, X Z; Bash, R; Balagurumoorthy, P et al. (2000) Conformational transition in DNA on a cold surface. Nucleic Acids Res 28:593-6
Leuba, S H; Bustamante, C (1999) Analysis of chromatin by scanning force microscopy. Methods Mol Biol 119:143-60
Nagaich, A K; Zhurkin, V B; Durell, S R et al. (1999) p53-induced DNA bending and twisting: p53 tetramer binds on the outer side of a DNA loop and increases DNA twisting. Proc Natl Acad Sci U S A 96:1875-80
Dlakic, M; Harrington, R E (1998) DIAMOD: display and modeling of DNA bending. Bioinformatics 14:326-31
Dlakic, M; Harrington, R E (1998) Unconventional helical phasing of repetitive DNA motifs reveals their relative bending contributions. Nucleic Acids Res 26:4274-9
Nagaich, A K; Appella, E; Harrington, R E (1997) DNA bending is essential for the site-specific recognition of DNA response elements by the DNA binding domain of the tumor suppressor protein p53. J Biol Chem 272:14842-9
Han, W; Dlakic, M; Zhu, Y J et al. (1997) Strained DNA is kinked by low concentrations of Zn2+. Proc Natl Acad Sci U S A 94:10565-70

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