Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
1R01CA070712-01A1
Application #
2114528
Study Section
Metabolic Pathology Study Section (MEP)
Project Start
1996-07-01
Project End
2001-04-30
Budget Start
1996-07-01
Budget End
1997-04-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas Health Science Center San Antonio
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
800772162
City
San Antonio
State
TX
Country
United States
Zip Code
78229
Ramamoorthy, Mahesh; Vaughan, Catherine; Deb, Sumitra et al. (2013) Measurement of chemosensitivity and growth rate in p53 expressing cells. Methods Mol Biol 962:127-33
Deb, Sumitra; Graves, Paul R (2013) Identification of novel mutant p53 interacting proteins by proteomic analysis. Methods Mol Biol 962:85-94
Vaughan, Catherine; Deb, Swati Palit; Deb, Sumitra (2013) Generation of p53 knock-down cell lines. Methods Mol Biol 962:193-9
Vaughan, Catherine A; Singh, Shilpa; Windle, Brad et al. (2012) p53 mutants induce transcription of NF-?B2 in H1299 cells through CBP and STAT binding on the NF-?B2 promoter and gain of function activity. Arch Biochem Biophys 518:79-88
Vaughan, Catherine A; Frum, Rebecca; Pearsall, Isabella et al. (2012) Allele specific gain-of-function activity of p53 mutants in lung cancer cells. Biochem Biophys Res Commun 428:6-10
Sankala, Heidi; Vaughan, Catherine; Wang, Jing et al. (2011) Upregulation of the mitochondrial transport protein, Tim50, by mutant p53 contributes to cell growth and chemoresistance. Arch Biochem Biophys 512:52-60
Frum, Rebecca; Ramamoorthy, Mahesh; Mohanraj, Lathika et al. (2009) MDM2 controls the timely expression of cyclin A to regulate the cell cycle. Mol Cancer Res 7:1253-67
Scian, M J; Carchman, E H; Mohanraj, L et al. (2008) Wild-type p53 and p73 negatively regulate expression of proliferation related genes. Oncogene 27:2583-93