Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
1R01CA071401-01
Application #
2115033
Study Section
Experimental Therapeutics Subcommittee 1 (ET)
Project Start
1996-08-15
Project End
1999-07-31
Budget Start
1996-08-15
Budget End
1997-07-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Maryland Baltimore
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
003255213
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Zhang, Jun; Yang, Jinbo; Roy, Sanjit K et al. (2003) The cell death regulator GRIM-19 is an inhibitor of signal transducer and activator of transcription 3. Proc Natl Acad Sci U S A 100:9342-7
Kalvakolanu, Dhananjaya V (2003) Alternate interferon signaling pathways. Pharmacol Ther 100:1-29
Ma, Xinrong; Hu, Junbo; Lindner, Daniel J et al. (2002) Mutational analysis of human thioredoxin reductase 1. Effects on p53-mediated gene expression and interferon and retinoic acid-induced cell death. J Biol Chem 277:22460-8
Karimpour, Shervin; Lou, Junyang; Lin, Lilie L et al. (2002) Thioredoxin reductase regulates AP-1 activity as well as thioredoxin nuclear localization via active cysteines in response to ionizing radiation. Oncogene 21:6317-27
Verma, Amit; Mohindru, Mani; Deb, Dilip K et al. (2002) Activation of Rac1 and the p38 mitogen-activated protein kinase pathway in response to arsenic trioxide. J Biol Chem 277:44988-95
Joshi, Vishwas D; Kalvakolanu, Dhananjaya V; Hebel, John R et al. (2002) Role of caspase 1 in murine antibacterial host defenses and lethal endotoxemia. Infect Immun 70:6896-903
Hu, Jiadi; Angell, Jon E; Zhang, Jun et al. (2002) Characterization of monoclonal antibodies against GRIM-19, a novel IFN-beta and retinoic acid-activated regulator of cell death. J Interferon Cytokine Res 22:1017-26
Morrison, Bei H; Bauer, Joseph A; Hu, Jiadi et al. (2002) Inositol hexakisphosphate kinase 2 sensitizes ovarian carcinoma cells to multiple cancer therapeutics. Oncogene 21:1882-9
Lindner, Daniel J; Ma, Xinrong; Hu, Jiadi et al. (2002) Thioredoxin reductase plays a critical role in IFN retinoid-mediated tumor-growth control in vivo. Clin Cancer Res 8:3210-8
Roy, Sanjit K; Hu, Junbo; Meng, Qingjun et al. (2002) MEKK1 plays a critical role in activating the transcription factor C/EBP-beta-dependent gene expression in response to IFN-gamma. Proc Natl Acad Sci U S A 99:7945-50

Showing the most recent 10 out of 25 publications