Putative Tumor Suppressor PTP1 in Breast Cancer

Mills, Gordon B.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: Research Project (R01)
• Project #: 1R01CA071418-01
• Application #: 2115047
• Study Section: Metabolic Pathology Study Section (MEP)
• Project Start: 1996-09-01
• Project End: 1999-08-31
• Budget Start: 1996-09-01
• Budget End: 1997-08-31
• Support Year: 1
• Fiscal Year: 1996

Institution

• Name: University of Texas MD Anderson Cancer Center
• Department: Genetics
• Type: Other Domestic Higher Education
• DUNS #: 001910777
• City: Houston
• State: TX
• Country: United States
• Zip Code: 77030

Publications

Cuevas, B; Lu, Y; Watt, S et al. (1999) SHP-1 regulates Lck-induced phosphatidylinositol 3-kinase phosphorylation and activity. J Biol Chem 274:27583-9

Lu, Y; Lin, Y Z; LaPushin, R et al. (1999) The PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and induces apoptosis and anoikis in breast cancer cells. Oncogene 18:7034-45

Davies, M A; Lu, Y; Sano, T et al. (1998) Adenoviral transgene expression of MMAC/PTEN in human glioma cells inhibits Akt activation and induces anoikis. Cancer Res 58:5285-90