Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
1R01CA071731-01
Application #
2115283
Study Section
Experimental Therapeutics Subcommittee 1 (ET)
Project Start
1996-07-12
Project End
1999-06-30
Budget Start
1996-07-12
Budget End
1997-06-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Pharmacology
Type
Schools of Medicine
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Lui, V W; He, Y; Huang, L (2001) Specific down-regulation of HER-2/neu mediated by a chimeric U6 hammerhead ribozyme results in growth inhibition of human ovarian carcinoma. Mol Ther 3:169-77
Li, S; Huang, L (2000) Nonviral gene therapy: promises and challenges. Gene Ther 7:31-4
Li, S; Tan, Y; Viroonchatapan, E et al. (2000) Targeted gene delivery to pulmonary endothelium by anti-PECAM antibody. Am J Physiol Lung Cell Mol Physiol 278:L504-11
Whitmore, M; Li, S; Huang, L (1999) LPD lipopolyplex initiates a potent cytokine response and inhibits tumor growth. Gene Ther 6:1867-75
Li, S; Wu, S P; Whitmore, M et al. (1999) Effect of immune response on gene transfer to the lung via systemic administration of cationic lipidic vectors. Am J Physiol 276:L796-804
Nikitin, A Y; Juarez-Perez, M I; Li, S et al. (1999) RB-mediated suppression of spontaneous multiple neuroendocrine neoplasia and lung metastases in Rb+/- mice. Proc Natl Acad Sci U S A 96:3916-21
Tan, Y; Li, S; Pitt, B R et al. (1999) The inhibitory role of CpG immunostimulatory motifs in cationic lipid vector-mediated transgene expression in vivo. Hum Gene Ther 10:2153-61
Brisson, M; He, Y; Li, S et al. (1999) A novel T7 RNA polymerase autogene for efficient cytoplasmic expression of target genes. Gene Ther 6:263-70
Yang, J P; Huang, L (1998) Time-dependent maturation of cationic liposome-DNA complex for serum resistance. Gene Ther 5:380-7
He, Y K; Lui, V W; Baar, J et al. (1998) Potentiation of E7 antisense RNA-induced antitumor immunity by co-delivery of IL-12 gene in HPV16 DNA-positive mouse tumor. Gene Ther 5:1462-71

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