Bleomycin Hydrolases - Proteases That Bind DNA

Joshua-Tor, Leemor

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: Research Project (R01)
• Project #: 1R01CA071746-01
• Application #: 2115296
• Study Section: Chemical Pathology Study Section (CPA)
• Project Start: 1996-08-01
• Project End: 1999-07-31
• Budget Start: 1996-08-01
• Budget End: 1997-07-31
• Support Year: 1
• Fiscal Year: 1996

Institution

• Name: Cold Spring Harbor Laboratory
• DUNS #: 065968786
• City: Cold Spring Harbor
• State: NY
• Country: United States
• Zip Code: 11724

Publications

O'Farrell, P A; Gonzalez, F; Zheng, W et al. (1999) Crystal structure of human bleomycin hydrolase, a self-compartmentalizing cysteine protease. Structure 7:619-27

Zheng, W; Johnston, S A; Joshua-Tor, L (1998) The unusual active site of Gal6/bleomycin hydrolase can act as a carboxypeptidase, aminopeptidase, and peptide ligase. Cell 93:103-9