Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
1R01CA072046-01
Application #
2115518
Study Section
Chemical Pathology Study Section (CPA)
Project Start
1996-08-20
Project End
1997-05-31
Budget Start
1996-08-20
Budget End
1997-05-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Beth Israel Deaconess Medical Center
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02215
Maulik, G; Botchway, S; Chakrabarti, S et al. (1999) Novel non-isotopic detection of MutY enzyme-recognized mismatches in DNA via ultrasensitive detection of aldehydes. Nucleic Acids Res 27:1316-22
Chakrabarti, S; Mahmood, A; Makrigiorgos, G M (1999) Fluorescent labelling of closely-spaced aldehydes induced in DNA by bleomycin-Fe(III). Int J Radiat Biol 75:1055-65
Botchway, S W; Chakrabarti, S; Makrigiorgos, G M (1998) Novel visible and ultraviolet light photogeneration of hydroxyl radicals by 2-methyl-4-nitro-quinoline-N-oxide (MNO) and 4,4'-dinitro-(2,2')bipyridinyl-N,N'-dioxide (DBD). Photochem Photobiol 67:635-40
Chakrabarti, S; Kassis, A I; Slayter, H S et al. (1998) Continuous detection of radiation or metal generated hydroxyl radicals within core chromatin particles. Int J Radiat Biol 73:53-63
Makrigiorgos, G M; Chakrabarti, S; Mahmood, A (1998) Fluorescent labelling of abasic sites: a novel methodology to detect closely-spaced damage sites in DNA. Int J Radiat Biol 74:99-109
Chakrabarti, S; Mahmood, A; Kassis, A I et al. (1996) Generation of hydroxyl radicals by nucleohistone-bound metal-adriamycin complexes. Free Radic Res 25:207-20