Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
1R01CA072079-01
Application #
2115544
Study Section
Chemical Pathology Study Section (CPA)
Project Start
1996-09-05
Project End
1999-08-31
Budget Start
1996-09-05
Budget End
1997-08-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Lawrence Berkeley National Laboratory
Department
Biology
Type
Organized Research Units
DUNS #
078576738
City
Berkeley
State
CA
Country
United States
Zip Code
94720
Rodriguez, Ben; Yang, Yanu; Guliaev, Anton B et al. (2010) Benzene-derived N2-(4-hydroxyphenyl)-deoxyguanosine adduct: UvrABC incision and its conformation in DNA. Toxicol Lett 193:26-32
Chenna, Ahmed; Gupta, Ramesh C; Bonala, Radha R et al. (2008) Synthesis of the fully protected phosphoramidite of the benzene-DNA adduct, N2-(4-Hydroxyphenyl)-2'-deoxyguanosine and incorporation of the later into DNA oligomers. Nucleosides Nucleotides Nucleic Acids 27:979-91
Hang, Bo; Guliaev, Anton B (2007) Substrate specificity of human thymine-DNA glycosylase on exocyclic cytosine adducts. Chem Biol Interact 165:230-8
Wang, Ping; Guliaev, Anton B; Elder, Rhoderick H et al. (2006) Alkylpurine-DNA-N-glycosylase excision of 7-(hydroxymethyl)-1,N6-ethenoadenine, a glycidaldehyde-derived DNA adduct. DNA Repair (Amst) 5:23-31
Wang, Ping; Guliaev, Anton B; Hang, Bo (2006) Metal inhibition of human N-methylpurine-DNA glycosylase activity in base excision repair. Toxicol Lett 166:237-47
Xie, Zhongwen; Zhang, Yangbin; Guliaev, Anton B et al. (2005) The p-benzoquinone DNA adducts derived from benzene are highly mutagenic. DNA Repair (Amst) 4:1399-409
Guliaev, Anton B; Singer, B; Hang, Bo (2004) Chloroethylnitrosourea-derived ethano cytosine and adenine adducts are substrates for Escherichia coli glycosylases excising analogous etheno adducts. DNA Repair (Amst) 3:1311-21
Guliaev, Anton B; Hang, Bo; Singer, B (2004) Structural insights by molecular dynamics simulations into specificity of the major human AP endonuclease toward the benzene-derived DNA adduct, pBQ-C. Nucleic Acids Res 32:2844-52
Hang, Bo (2004) Repair of exocyclic DNA adducts: rings of complexity. Bioessays 26:1195-208
Hang, Bo; Singer, B (2003) Protein-protein interactions involving DNA glycosylases. Chem Res Toxicol 16:1181-95

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