Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
1R01CA072156-01
Application #
2115577
Study Section
Special Emphasis Panel (ZRG2-ET-1 (03))
Project Start
1996-07-01
Project End
2000-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas MD Anderson Cancer Center
Department
Radiation-Diagnostic/Oncology
Type
Other Domestic Higher Education
DUNS #
001910777
City
Houston
State
TX
Country
United States
Zip Code
77030
Rosenthal, Rosalind A; Fish, Brian; Hill, Richard P et al. (2011) Salen Mn complexes mitigate radiation injury in normal tissues. Anticancer Agents Med Chem 11:359-72
Raju, U; Gumin, G J; Tofilon, P J (2000) Radiation-induced transcription factor activation in the rat cerebral cortex. Int J Radiat Biol 76:1045-53
Tofilon, P J; Fike, J R (2000) The radioresponse of the central nervous system: a dynamic process. Radiat Res 153:357-70
Raju, U; Gumin, G J; Tofilon, P J (1999) NF kappa B activity and target gene expression in the rat brain after one and two exposures to ionizing radiation. Radiat Oncol Investig 7:145-52
Noel, F; Raju, U; Happel, E et al. (1999) X-irradiation-induced loss of O-2A progenitor cells in rat spinal cord is inhibited by implants of cells engineered to secrete glial growth factor 2. Neuroreport 10:535-40
Noel, F; Gumin, G J; Raju, U et al. (1998) Increased expression of prohormone convertase-2 in the irradiated rat brain. FASEB J 12:1725-30
Raju, U; Gumin, G J; Noel, F et al. (1998) IkappaBalpha degradation is not a requirement for the X-ray-induced activation of nuclear factor kappaB in normal rat astrocytes and human brain tumour cells. Int J Radiat Biol 74:617-24
Noel, F; Tofilon, P J (1998) Astrocytes protect against X-ray-induced neuronal toxicity in vitro. Neuroreport 9:1133-7
Hayakawa, K; Borchardt, P E; Sakuma, S et al. (1997) Microglial cytokine gene induction after irradiation is affected by morphologic differentiation. Radiat Med 15:405-10
Noel, F; Ijichi, A; Chen, J J et al. (1997) X-ray-mediated reduction in basic fibroblast growth factor expression in primary rat astrocyte cultures. Radiat Res 147:484-9

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