Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA072274-01S1
Application #
2356299
Study Section
Special Emphasis Panel (SRC (28))
Project Start
1996-07-01
Project End
2001-04-30
Budget Start
1996-07-01
Budget End
1997-04-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Nebraska Medical Center
Department
Biochemistry
Type
Schools of Medicine
DUNS #
City
Omaha
State
NE
Country
United States
Zip Code
68198
Zhang, Xiu-Qing; Kondrikov, Dmitry; Yuan, Ta-Chun et al. (2003) Receptor protein tyrosine phosphatase alpha signaling is involved in androgen depletion-induced neuroendocrine differentiation of androgen-sensitive LNCaP human prostate cancer cells. Oncogene 22:6704-16
Igawa, Tsukasa; Lin, Fen-Fen; Rao, Prathibha et al. (2003) Suppression of LNCaP prostate cancer xenograft tumors by a prostate-specific protein tyrosine phosphatase, prostatic acid phosphatase. Prostate 55:247-58
Igawa, Tsukasa; Lin, Fen-Fen; Lee, Ming-Shyue et al. (2002) Establishment and characterization of androgen-independent human prostate cancer LNCaP cell model. Prostate 50:222-35
Lin, M F; Lee, M S; Zhou, X W et al. (2001) Decreased expression of cellular prostatic acid phosphatase increases tumorigenicity of human prostate cancer cells. J Urol 166:1943-50
Zelivianski, S; Verni, M; Moore, C et al. (2001) Multipathways for transdifferentiation of human prostate cancer cells into neuroendocrine-like phenotype. Biochim Biophys Acta 1539:28-43
Zhang, X Q; Lee, M S; Zelivianski, S et al. (2001) Characterization of a prostate-specific tyrosine phosphatase by mutagenesis and expression in human prostate cancer cells. J Biol Chem 276:2544-50
Karan, D; Johansson, S L; Lin, M F et al. (2001) Expression of tumor-associated glycoprotein-72 (TAG-72) antigen in human prostatic adenocarcinomas. Oncol Rep 8:1123-6
Lin, M F; Zhang, X Q; Dean, J et al. (2001) Protein kinase C pathway is involved in regulating the secretion of prostatic acid phosphatase in human prostate cancer cells. Cell Biol Int 25:1139-48
Zelivianski, S; Larson, C; Seberger, J et al. (2000) Expression of human prostatic acid phosphatase gene is regulated by upstream negative and positive elements. Biochim Biophys Acta 1491:123-32
Lin, M F; Lee, M S; Garcia-Arenas, R et al. (2000) Differential responsiveness of prostatic acid phosphatase and prostate-specific antigen mRNA to androgen in prostate cancer cells. Cell Biol Int 24:681-9

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