Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA072763-02S1
Application #
2873276
Study Section
General Medicine A Subcommittee 2 (GMA)
Program Officer
Spalholz, Barbara A
Project Start
1997-03-15
Project End
2000-12-31
Budget Start
1998-01-01
Budget End
1998-10-31
Support Year
2
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Boston University
Department
Dermatology
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02118
Park, Hee-Young; Wu, Heng; Killoran, Christina E et al. (2004) The receptor for activated C-kinase-I (RACK-I) anchors activated PKC-beta on melanosomes. J Cell Sci 117:3659-68
Park, Hee-Young; Lee, Jin; Gonzalez, Salvador et al. (2004) Topical application of a protein kinase C inhibitor reduces skin and hair pigmentation. J Invest Dermatol 122:159-66
Wu, Heng; Park, Hee-Young (2003) Protein kinase C-beta-mediated complex formation between tyrosinase and TRP-1. Biochem Biophys Res Commun 311:948-53
Park, H Y; Gilchrest, B A (1999) Signaling pathways mediating melanogenesis. Cell Mol Biol (Noisy-le-grand) 45:919-30
Park, H Y; Perez, J M; Laursen, R et al. (1999) Protein kinase C-beta activates tyrosinase by phosphorylating serine residues in its cytoplasmic domain. J Biol Chem 274:16470-8
Ouahes, N; Phillips, T J; Park, H Y (1998) Expression of c-fos and c-Ha-ras proto-oncogenes is induced in human chronic wounds. Dermatol Surg 24:1354-7;discussion 1358
Ao, Y; Park, H Y; Olaizola-Horn, S et al. (1998) Activation of cAMP-dependent protein kinase is required for optimal alpha-melanocyte-stimulating hormone-induced pigmentation. Exp Cell Res 244:117-24