Benbrook, Doris M; Kamelle, Scott A; Guruswamy, Suresh B et al. (2005) Flexible heteroarotinoids (Flex-Hets) exhibit improved therapeutic ratios as anti-cancer agents over retinoic acid receptor agonists. Invest New Drugs 23:417-28
|
Brown, Chad W; Liu, Shengquan; Klucik, Jozef et al. (2004) Novel heteroarotinoids as potential antagonists of Mycobacterium bovis BCG. J Med Chem 47:1008-17
|
Liu, Shengquan; Brown, Chad W; Berlin, K Darrell et al. (2004) Synthesis of flexible sulfur-containing heteroarotinoids that induce apoptosis and reactive oxygen species with discrimination between malignant and benign cells. J Med Chem 47:999-1007
|
Dhar, A; Liu, S; Klucik, J et al. (1999) Synthesis, structure-activity relationships, and RARgamma-ligand interactions of nitrogen heteroarotinoids. J Med Chem 42:3602-14
|
Zacheis, D; Dhar, A; Lu, S et al. (1999) Heteroarotinoids inhibit head and neck cancer cell lines in vitro and in vivo through both RAR and RXR retinoic acid receptors. J Med Chem 42:4434-45
|
Benbrook, D M; Subramanian, S; Gale, J B et al. (1998) Synthesis and characterization of heteroarotinoids demonstrate structure specificity relationships. J Med Chem 41:3753-7
|
Benbrook, D M; Madler, M M; Spruce, L W et al. (1997) Biologically active heteroarotinoids exhibiting anticancer activity and decreased toxicity. J Med Chem 40:3567-83
|
Benbrook, D M; Shen-Gunther, J; Nunez, E R et al. (1997) Differential retinoic acid radiosensitization of cervical carcinoma cell lines. Clin Cancer Res 3:939-45
|