Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA074435-02
Application #
2654289
Study Section
Immunobiology Study Section (IMB)
Program Officer
Mccarthy, Susan A
Project Start
1997-02-12
Project End
2002-01-31
Budget Start
1998-02-01
Budget End
1999-01-31
Support Year
2
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Sidney Kimmel Cancer Center
Department
Type
DUNS #
City
San Diego
State
CA
Country
United States
Zip Code
92121
Jung, Barbara; Barbier, Valerie; Brickner, Howard et al. (2005) Mechanisms of sulindac-induced apoptosis and cell cycle arrest. Cancer Lett 219:15-25
Fotedar, Rati; Bendjennat, Mourad; Fotedar, Arun (2004) Functional analysis of CDK inhibitor p21WAF1. Methods Mol Biol 281:55-71
Pennaneach, Vincent; Barbier, Valerie; Regazzoni, Karine et al. (2004) Rb inhibits E2F-1-induced cell death in a LXCXE-dependent manner by active repression. J Biol Chem 279:23376-83
Fotedar, Rati; Bendjennat, Mourad; Fotedar, Arun (2004) Role of p21WAF1 in the cellular response to UV. Cell Cycle 3:134-7
Munshi, Anil; Cannella, Dominique; Brickner, Howard et al. (2003) Cell cycle-dependent phosphorylation of the large subunit of replication factor C (RF-C) leads to its dissociation from the RF-C complex. J Biol Chem 278:48467-73
Bendjennat, Mourad; Boulaire, Jerome; Jascur, Thomas et al. (2003) UV irradiation triggers ubiquitin-dependent degradation of p21(WAF1) to promote DNA repair. Cell 114:599-610
Salles-Passador, Isabelle; Munshi, Anil; Cannella, Dominique et al. (2003) Phosphorylation of the PCNA binding domain of the large subunit of replication factor C on Thr506 by cyclin-dependent kinases regulates binding to PCNA. Nucleic Acids Res 31:5202-11
Stromblad, Staffan; Fotedar, Arun; Brickner, Howard et al. (2002) Loss of p53 compensates for alpha v-integrin function in retinal neovascularization. J Biol Chem 277:13371-4
Pennaneach, V; Salles-Passador, I; Munshi, A et al. (2001) The large subunit of replication factor C promotes cell survival after DNA damage in an LxCxE motif- and Rb-dependent manner. Mol Cell 7:715-27
Boulaire, J; Fotedar, A; Fotedar, R (2000) The functions of the cdk-cyclin kinase inhibitor p21WAF1. Pathol Biol (Paris) 48:190-202

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