Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA075350-04
Application #
6489107
Study Section
Experimental Therapeutics Subcommittee 1 (ET)
Program Officer
Forry, Suzanne L
Project Start
1999-01-01
Project End
2004-12-31
Budget Start
2002-01-01
Budget End
2004-12-31
Support Year
4
Fiscal Year
2002
Total Cost
$230,217
Indirect Cost

  Institution

Name
Wake Forest University Health Sciences
Department
Biochemistry
Type
Schools of Medicine
DUNS #
937727907
City
Winston-Salem
State
NC
Country
United States
Zip Code
27157

  Publications

DeRose, Eugene F; Darden, Thomas; Harvey, Scott et al. (2003) Elucidation of the epsilon-theta subunit interface of Escherichia coli DNA polymerase III by NMR spectroscopy. Biochemistry 42:3635-44
DeRose, Eugene F; Li, Dawei; Darden, Thomas et al. (2002) Model for the catalytic domain of the proofreading epsilon subunit of Escherichia coli DNA polymerase III based on NMR structural data. Biochemistry 41:94-110
Mazur, D J; Perrino, F W (2001) Structure and expression of the TREX1 and TREX2 3' --> 5' exonuclease genes. J Biol Chem 276:14718-27
Mazur, D J; Perrino, F W (2001) Excision of 3' termini by the Trex1 and TREX2 3'-->5' exonucleases. Characterization of the recombinant proteins. J Biol Chem 276:17022-9
Mazur, D J; Perrino, F W (1999) Identification and expression of the TREX1 and TREX2 cDNA sequences encoding mammalian 3'-->5' exonucleases. J Biol Chem 274:19655-60
Perrino, F W; Mazur, D J; Ward, H et al. (1999) Exonucleases and the incorporation of aranucleotides into DNA. Cell Biochem Biophys 30:331-52
Perrino, F W; Harvey, S; McNeill, S M (1999) Two functional domains of the epsilon subunit of DNA polymerase III. Biochemistry 38:16001-9