Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA076528-02
Application #
6172953
Study Section
Chemical Pathology Study Section (CPA)
Program Officer
Okano, Paul
Project Start
1999-07-01
Project End
2004-04-30
Budget Start
2000-05-01
Budget End
2001-04-30
Support Year
2
Fiscal Year
2000
Total Cost
$241,707
Indirect Cost
Name
Oregon Health and Science University
Department
Neurosciences
Type
Schools of Medicine
DUNS #
009584210
City
Portland
State
OR
Country
United States
Zip Code
97239
Skinner, Amy M; Turker, Mitchell S (2008) High frequency induction of CC to TT tandem mutations in DNA repair-proficient mammalian cells. Photochem Photobiol 84:222-7
Skinner, Amy M; Dan, Cristian; Turker, Mitchell S (2008) The frequency of CC to TT tandem mutations in mismatch repair-deficient cells is increased in a cytosine run. Mutagenesis 23:87-91
Kasameyer, Elizabeth; Connolly, Lanelle; Lasarev, Michael et al. (2008) The spectra of large second-step mutations are similar for two different mouse autosomes. Mutat Res 637:66-72
Turker, Mitchell S; Lasarev, Michael; Connolly, Lanelle et al. (2007) Age-related accumulation of autosomal mutations in solid tissues of the mouse is gender and cell type specific. Aging Cell 6:73-86
Wang, Qi; Ponomareva, Olga N; Lasarev, Michael et al. (2006) High frequency induction of mitotic recombination by ionizing radiation in Mlh1 null mouse cells. Mutat Res 594:189-98
Shin-Darlak, Chi Y; Skinner, Amy M; Turker, Mitchell S (2005) A role for Pms2 in the prevention of tandem CC --> TT substitutions induced by ultraviolet radiation and oxidative stress. DNA Repair (Amst) 4:51-7
Turker, Mitchell S; Schwartz, Jeffrey L; Jordan, Robert et al. (2004) Persistence of chromatid aberrations in the cells of solid mouse tissues exposed to 137Cs gamma radiation. Radiat Res 162:357-64
Turker, Mitchell S (2003) Autosomal mutation in somatic cells of the mouse. Mutagenesis 18:1-6
Yates, Phillip A; Burman, Robert; Simpson, James et al. (2003) Silencing of mouse Aprt is a gradual process in differentiated cells. Mol Cell Biol 23:4461-70
Shin, Chi Y; Turker, Mitchell S (2002) A:T --> G:C base pair substitutions occur at a higher rate than other substitution events in Pms2 deficient mouse cells. DNA Repair (Amst) 1:995-1001

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