Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
7R01CA076639-02
Application #
6038404
Study Section
Reproductive Endocrinology Study Section (REN)
Program Officer
Mohla, Suresh
Project Start
1998-11-11
Project End
2002-11-30
Budget Start
1998-11-11
Budget End
1998-11-30
Support Year
2
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Mcp Hahnemann University
Department
Pathology
Type
Schools of Medicine
DUNS #
City
Philadelphia
State
PA
Country
United States
Zip Code
19102
Wang, Min; Hu, Youji; Amatangelo, Michael D et al. (2011) Role of ribosomal protein RPS2 in controlling let-7a expression in human prostate cancer. Mol Cancer Res 9:36-50
Stearns, Mark E; Wang, Min (2011) Synergistic Effects of the Green Tea Extract Epigallocatechin-3-gallate and Taxane in Eradication of Malignant Human Prostate Tumors. Transl Oncol 4:147-56
Stearns, Mark E; Amatangelo, Michael D; Varma, Devika et al. (2010) Combination therapy with epigallocatechin-3-gallate and doxorubicin in human prostate tumor modeling studies: inhibition of metastatic tumor growth in severe combined immunodeficiency mice. Am J Pathol 177:3169-79
Goodyear, S M; Amatangelo, M D; Stearns, M E (2009) Dysplasia of human prostate CD133(hi) sub-population in NOD-SCIDS is blocked by c-myc anti-sense. Prostate 69:689-98
Dolloff, Nathan G; Shulby, Shannon S; Nelson, Autumn V et al. (2005) Bone-metastatic potential of human prostate cancer cells correlates with Akt/PKB activation by alpha platelet-derived growth factor receptor. Oncogene 24:6848-54
Stearns, Mark; Tran, Jordan; Francis, Mary Kay et al. (2005) Activated Ras enhances insulin-like growth factor I induction of vascular endothelial growth factor in prostate epithelial cells. Cancer Res 65:2085-8
Shulby, Shannon A; Dolloff, Nathan G; Stearns, Mark E et al. (2004) CX3CR1-fractalkine expression regulates cellular mechanisms involved in adhesion, migration, and survival of human prostate cancer cells. Cancer Res 64:4693-8
Stearns, Mark E; Wang, M; Hu, Youji et al. (2003) Interleukin-10 activation of the interleukin-10E1 pathway and tissue inhibitor of metalloproteinase-1 expression is enhanced by proteasome inhibitors in primary prostate tumor lines. Mol Cancer Res 1:631-42
Wang, M; Hu, Y; Stearns, M E (2003) A novel IL-10 signalling mechanism regulates TIMP-1 expression in human prostate tumour cells. Br J Cancer 88:1605-14
Aoyagi, K; Shima, I; Wang, M et al. (1998) Specific transcription factors prognostic for prostate cancer progression. Clin Cancer Res 4:2153-60

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