Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA077656-06
Application #
6698055
Study Section
Metabolic Pathology Study Section (MEP)
Program Officer
Jhappan, Chamelli
Project Start
1998-05-01
Project End
2007-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
6
Fiscal Year
2004
Total Cost
$352,109
Indirect Cost
Name
Roswell Park Cancer Institute Corp
Department
Type
DUNS #
824771034
City
Buffalo
State
NY
Country
United States
Zip Code
14263
Ramirez, Robert A; Lee, Amy; Schedin, Pepper et al. (2012) Alterations in mast cell frequency and relationship to angiogenesis in the rat mammary gland during windows of physiologic tissue remodeling. Dev Dyn 241:890-900
Warren, Mary Ann; Shoemaker, Suzanne F; Shealy, David J et al. (2009) Tumor necrosis factor deficiency inhibits mammary tumorigenesis and a tumor necrosis factor neutralizing antibody decreases mammary tumor growth in neu/erbB2 transgenic mice. Mol Cancer Ther 8:2655-63
Zhang, Jiping; Warren, Mary Ann; Shoemaker, Suzanne F et al. (2007) NFkappaB1/p50 is not required for tumor necrosis factor-stimulated growth of primary mammary epithelial cells: implications for NFkappaB2/p52 and RelB. Endocrinology 148:268-78
Zhang, Haitao; Zhang, Haiwei; Lee, Laura et al. (2004) The liver-enriched inhibitory protein isoform of CCAAT/enhancer-binding protein beta, but not nuclear factor-kappaB, mediates the transcriptional inhibition of beta-casein by tumor necrosis factor-alpha. Endocrinology 145:2833-44
Shea-Eaton, W K; Lee, P P; Ip, M M (2001) Regulation of milk protein gene expression in normal mammary epithelial cells by tumor necrosis factor. Endocrinology 142:2558-68
Berleth, E S; Masso-Welch, P A; Kazim, L A et al. (2001) Expression, tissue distribution, and cellular localization of the antiapoptotic TIP-B1 protein. J Leukoc Biol 69:995-1005
Lee, P P; Hwang, J J; Mead, L et al. (2001) Functional role of matrix metalloproteinases (MMPs) in mammary epithelial cell development. J Cell Physiol 188:75-88
Varela, L M; Stangle-Castor, N C; Shoemaker, S F et al. (2001) TNFalpha induces NFkappaB/p50 in association with the growth and morphogenesis of normal and transformed rat mammary epithelial cells. J Cell Physiol 188:120-31
Lee, P P; Hwang, J J; Murphy, G et al. (2000) Functional significance of MMP-9 in tumor necrosis factor-induced proliferation and branching morphogenesis of mammary epithelial cells. Endocrinology 141:3764-73