Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
1R01CA079955-01
Application #
2739808
Study Section
Special Emphasis Panel (ZRG2-ET-1 (05))
Program Officer
Wu, Roy S
Project Start
1999-04-01
Project End
2002-03-31
Budget Start
1999-04-01
Budget End
2000-04-13
Support Year
1
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
168559177
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Perez-Mancera, P A; Sanchez-Garcia, I (2005) Understanding mesenchymal cancer: the liposarcoma-associated FUS-DDIT3 fusion gene as a model. Semin Cancer Biol 15:206-14
Perez-Losada, Jesus; Sanchez-Martin, Manuel; Perez-Caro, Maria et al. (2003) The radioresistance biological function of the SCF/kit signaling pathway is mediated by the zinc-finger transcription factor Slug. Oncogene 22:4205-11
Sanchez-Martin, Manuel; Perez-Losada, Jesus; Rodriguez-Garcia, Arancha et al. (2003) Deletion of the SLUG (SNAI2) gene results in human piebaldism. Am J Med Genet A 122A:125-32
Perez-Mancera, Pedro Antonio; Perez-Losada, Jesus; Sanchez-Martin, Manuel et al. (2002) Expression of the FUS domain restores liposarcoma development in CHOP transgenic mice. Oncogene 21:1679-84
Sanchez-Martin, Manuel; Rodriguez-Garcia, Arancha; Perez-Losada, Jesus et al. (2002) SLUG (SNAI2) deletions in patients with Waardenburg disease. Hum Mol Genet 11:3231-6
Perez-Losada, Jesus; Sanchez-Martin, Manuel; Rodriguez-Garcia, Arancha et al. (2002) Zinc-finger transcription factor Slug contributes to the function of the stem cell factor c-kit signaling pathway. Blood 100:1274-86
Rodriguez-Garcia, A; Sanchez-Martin, M; Perez-Losada, J et al. (2001) Selective destruction of tumor cells through specific inhibition of products resulting from chromosomal translocations. Curr Cancer Drug Targets 1:109-19
Perez-Losada, J; Gutierrez-Cianca, N; Sanchez-Garcia, I (2001) Philadelphia-positive B-cell acute lymphoblastic leukemia is initiated in an uncommitted progenitor cell. Leuk Lymphoma 42:569-76
Cobaleda, C; Sanchez-Garcia, I (2001) RNase P: from biological function to biotechnological applications. Trends Biotechnol 19:406-11
Cobaleda, C; Gutierrez-Cianca, N; Perez-Losada, J et al. (2000) A primitive hematopoietic cell is the target for the leukemic transformation in human philadelphia-positive acute lymphoblastic leukemia. Blood 95:1007-13

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