Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA080145-03
Application #
6329073
Study Section
Radiation Study Section (RAD)
Program Officer
Wolpert, Mary K
Project Start
1999-04-22
Project End
2002-11-30
Budget Start
2000-12-01
Budget End
2001-11-30
Support Year
3
Fiscal Year
2001
Total Cost
$225,526
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Zielske, Steven P; Livant, Donna L; Lawrence, Theodore S (2009) Radiation increases invasion of gene-modified mesenchymal stem cells into tumors. Int J Radiat Oncol Biol Phys 75:843-53
Abela, R A; Qian, J; Xu, L et al. (2008) Radiation improves gene delivery by a novel transferrin-lipoplex nanoparticle selectively in cancer cells. Cancer Gene Ther 15:496-507
Zhang, Ming; Qian, Jun; Xing, Xianying et al. (2008) Inhibition of the tumor necrosis factor-alpha pathway is radioprotective for the lung. Clin Cancer Res 14:1868-76
Huang, Xiao W; Yang, Jiong; Dragovic, Aleksandar F et al. (2006) Antisense oligonucleotide inhibition of tumor necrosis factor receptor 1 protects the liver from radiation-induced apoptosis. Clin Cancer Res 12:2849-55
Huang, Xiao W; Tang, Zhao Y; Lawrence, Theodore S et al. (2005) 5-fluorouracil and hydroxyurea enhance adenovirus-mediated transgene expression in colon and hepatocellular carcinoma cells. J Cancer Res Clin Oncol 131:184-90
Qian, Jun; Yang, Jiong; Dragovic, Aleksandar F et al. (2005) Ionizing radiation-induced adenovirus infection is mediated by Dynamin 2. Cancer Res 65:5493-7
Huang, Xiao W; Lieber, Andre; Tang, Zhao Y et al. (2004) Gene expression in intrahepatic tumors through DNA recombination by a replication-activated adenovirus vector. Cancer Gene Ther 11:450-6
Rehemtulla, Alnawaz; Hamstra, Daniel A; Kievit, Els et al. (2004) Extracellular expression of cytosine deaminase results in increased 5-FU production for enhanced enzyme/prodrug therapy. Anticancer Res 24:1393-9
Zhang, Ming; Li, Shengping; Nyati, Mukesh K et al. (2003) Regional delivery and selective expression of a high-activity yeast cytosine deaminase in an intrahepatic colon cancer model. Cancer Res 63:658-63
Zhang, Ming; Li, Shengping; Li, Jun et al. (2003) Ionizing radiation increases adenovirus uptake and improves transgene expression in intrahepatic colon cancer xenografts. Mol Ther 8:21-8

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