Melanoma Associated T and DC Dysfunction and Death

Storkus, Walter J.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: Research Project (R01)
• Project #: 5R01CA080216-02
• Application #: 6362692
• Study Section: Special Emphasis Panel (ZRG1-SSS-4 (01))
• Program Officer: Xie, Heng
• Project Start: 2000-03-01
• Project End: 2005-02-28
• Budget Start: 2001-03-01
• Budget End: 2002-02-28
• Support Year: 2
• Fiscal Year: 2001
• Total Cost: $303,750

Institution

• Name: University of Pittsburgh
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• DUNS #: 053785812
• City: Pittsburgh
• State: PA
• Country: United States
• Zip Code: 15213

Publications

Wesa, Amy; Kalinski, Pawel; Kirkwood, John M et al. (2007) Polarized type-1 dendritic cells (DC1) producing high levels of IL-12 family members rescue patient TH1-type antimelanoma CD4+ T cell responses in vitro. J Immunother 30:75-82

Mailliard, Robbie B; Son, Young-Ik; Redlinger, Richard et al. (2003) Dendritic cells mediate NK cell help for Th1 and CTL responses: two-signal requirement for the induction of NK cell helper function. J Immunol 171:2366-73

O'Connell, Peta J; Son, Young-Ik; Giermasz, Adam et al. (2003) Type-1 polarized nature of mouse liver CD8alpha- and CD8alpha+ dendritic cells: tissue-dependent differences offset CD8alpha-related dendritic cell heterogeneity. Eur J Immunol 33:2007-13