Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA080233-02
Application #
6137724
Study Section
Experimental Therapeutics Subcommittee 1 (ET)
Program Officer
Wolpert, Mary K
Project Start
1999-01-01
Project End
2000-02-29
Budget Start
2000-01-01
Budget End
2000-02-29
Support Year
2
Fiscal Year
2000
Total Cost
$34,265
Indirect Cost
Name
Cleveland Clinic Lerner
Department
Type
DUNS #
017730458
City
Cleveland
State
OH
Country
United States
Zip Code
44195
Kanzawa, Takao; Komata, Tadashi; Kyo, Satoru et al. (2003) Down-regulation of telomerase activity in malignant glioma cells by p27KIP1. Int J Oncol 23:1703-8
Komata, Tadashi; Kanzawa, Takao; Kondo, Yasuko et al. (2002) Telomerase as a therapeutic target for malignant gliomas. Oncogene 21:656-63
Kondo, Y; Komata, T; Kondo, S (2001) Combination therapy of 2-5A antisense against telomerase RNA and cisplatin for malignant gliomas. Int J Oncol 18:1287-92
Mukai, S; Kondo, Y; Koga, S et al. (2000) 2-5A antisense telomerase RNA therapy for intracranial malignant gliomas. Cancer Res 60:4461-7
Kondo, Y; Koga, S; Komata, T et al. (2000) Treatment of prostate cancer in vitro and in vivo with 2-5A-anti-telomerase RNA component. Oncogene 19:2205-11
Komata, T; Kondo, Y; Koga, S et al. (2000) Combination therapy of malignant glioma cells with 2-5A-antisense telomerase RNA and recombinant adenovirus p53. Gene Ther 7:2071-9