Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA082257-03
Application #
6377313
Study Section
Molecular Biology Study Section (MBY)
Program Officer
Pelroy, Richard
Project Start
1999-07-01
Project End
2004-04-30
Budget Start
2001-05-01
Budget End
2002-04-30
Support Year
3
Fiscal Year
2001
Total Cost
$235,824
Indirect Cost
Name
Yale University
Department
Pathology
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Liu, Jinping; Luo, Shukun; Zhao, Hongchang et al. (2012) Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain. Nucleic Acids Res 40:3898-912
Wilson, Kathleen A; Colavito, Sierra A; Schulz, Vincent et al. (2011) NFBD1/MDC1 regulates Cav1 and Cav2 independently of DNA damage and p53. Mol Cancer Res 9:766-81
Mok, Janine; Kim, Philip M; Lam, Hugo Y K et al. (2010) Deciphering protein kinase specificity through large-scale analysis of yeast phosphorylation site motifs. Sci Signal 3:ra12
Golan, Amnon; Pick, Elah; Tsvetkov, Lyuben et al. (2010) Centrosomal Chk2 in DNA damage responses and cell cycle progression. Cell Cycle 9:2647-56
Stern, David F (2009) BRCTing up is hard to do. Mol Cell 33:137-8
Wilson, Kathleen A; Stern, David F (2008) NFBD1/MDC1, 53BP1 and BRCA1 have both redundant and unique roles in the ATM pathway. Cell Cycle 7:3584-94
Jia-Lin Ma, Nianhan; Stern, David F (2008) Regulation of the Rad53 protein kinase in signal amplification by oligomer assembly and disassembly. Cell Cycle 7:808-17
Ma, Jia-Lin; Lee, Soo-Jung; Duong, Jimmy K et al. (2006) Activation of the checkpoint kinase Rad53 by the phosphatidyl inositol kinase-like kinase Mec1. J Biol Chem 281:3954-63
Li, Jia; Stern, David F (2005) DNA damage regulates Chk2 association with chromatin. J Biol Chem 280:37948-56
Tsvetkov, Lyuben; Stern, David F (2005) Phosphorylation of Plk1 at S137 and T210 is inhibited in response to DNA damage. Cell Cycle 4:166-71

Showing the most recent 10 out of 22 publications