Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
1R01CA082511-01
Application #
2885542
Study Section
Reproductive Endocrinology Study Section (REN)
Program Officer
Mohla, Suresh
Project Start
1999-07-01
Project End
2003-04-30
Budget Start
1999-07-01
Budget End
2000-04-30
Support Year
1
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of Alabama Birmingham
Department
Physiology
Type
Schools of Medicine
DUNS #
004514360
City
Birmingham
State
AL
Country
United States
Zip Code
35294
El-Naggar, Shahenda M; Malik, Mohammed T; Kakar, Sham S (2007) Small interfering RNA against PTTG: a novel therapy for ovarian cancer. Int J Oncol 31:137-43
El-Naggar, Shahenda M; Malik, Mohammad T; Martin, Alvin et al. (2007) Development of cystic glandular hyperplasia of the endometrium in Mullerian inhibitory substance type II receptor-pituitary tumor transforming gene transgenic mice. J Endocrinol 194:179-91
Bradshaw, C; Kakar, S S (2007) Pituitary tumor transforming gene: an important gene in normal cellular functions and tumorigenesis. Histol Histopathol 22:219-26
Malik, Mohammad T; Kakar, Sham S (2006) Regulation of angiogenesis and invasion by human Pituitary tumor transforming gene (PTTG) through increased expression and secretion of matrix metalloproteinase-2 (MMP-2). Mol Cancer 5:61
Puri, R; Tousson, A; Chen, L et al. (2001) Molecular cloning of pituitary tumor transforming gene 1 from ovarian tumors and its expression in tumors. Cancer Lett 163:131-9
Kakar, S S; Chen, L; Puri, R et al. (2001) Characterization of a polyclonal antibody to human pituitary tumor transforming gene 1 (PTTG1) protein. J Histochem Cytochem 49:1537-46
Chen, L; Puri, R; Lefkowitz, E J et al. (2000) Identification of the human pituitary tumor transforming gene (hPTTG) family: molecular structure, expression, and chromosomal localization. Gene 248:41-50
Kakar, S S (1999) Molecular cloning, genomic organization, and identification of the promoter for the human pituitary tumor transforming gene (PTTG). Gene 240:317-24