Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA085560-04
Application #
6655505
Study Section
Metabolic Pathology Study Section (MEP)
Program Officer
Okano, Paul
Project Start
2000-04-01
Project End
2005-03-31
Budget Start
2003-04-01
Budget End
2004-03-31
Support Year
4
Fiscal Year
2003
Total Cost
$273,600
Indirect Cost
Name
Emory University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
066469933
City
Atlanta
State
GA
Country
United States
Zip Code
30322
Sun, Xiaodong; Li, Jie; Sica, Gabriel et al. (2013) Interruption of nuclear localization of ATBF1 during the histopathologic progression of head and neck squamous cell carcinoma. Head Neck 35:1007-14
Dong, Xue-Yuan; Fu, Xiaoying; Fan, Songqing et al. (2012) Oestrogen causes ATBF1 protein degradation through the oestrogen-responsive E3 ubiquitin ligase EFP. Biochem J 444:581-90
Su, Dan; Fu, Xiaoying; Fan, Songqing et al. (2012) Role of ERRF, a novel ER-related nuclear factor, in the growth control of ER-positive human breast cancer cells. Am J Pathol 180:1189-201
Dong, Xue-Yuan; Guo, Peng; Sun, Xiaodong et al. (2011) Estrogen up-regulates ATBF1 transcription but causes its protein degradation in estrogen receptor-alpha-positive breast cancer cells. J Biol Chem 286:13879-90
Dong, Xue-Yuan; Sun, Xiaodong; Guo, Peng et al. (2010) ATBF1 inhibits estrogen receptor (ER) function by selectively competing with AIB1 for binding to the ER in ER-positive breast cancer cells. J Biol Chem 285:32801-9
Dong, Xue-Yuan; Guo, Peng; Boyd, Jeff et al. (2009) Implication of snoRNA U50 in human breast cancer. J Genet Genomics 36:447-54
Chen, Ling; Zhu, Zhengmao; Sun, Xiaodong et al. (2009) Down-regulation of tumor suppressor gene FEZ1/LZTS1 in breast carcinoma involves promoter methylation and associates with metastasis. Breast Cancer Res Treat 116:471-8
Dong, Xue-Yuan; Rodriguez, Carmen; Guo, Peng et al. (2008) SnoRNA U50 is a candidate tumor-suppressor gene at 6q14.3 with a mutation associated with clinically significant prostate cancer. Hum Mol Genet 17:1031-42
Sun, Xiaodong; Zhou, Yingfa; Otto, Kristen B et al. (2007) Infrequent mutation of ATBF1 in human breast cancer. J Cancer Res Clin Oncol 133:103-5
Sun, Xiaodong; Chen, Ceshi; Vessella, Robert L et al. (2006) Microsatellite instability and mismatch repair target gene mutations in cell lines and xenografts of prostate cancer. Prostate 66:660-6

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