|
Kumar, Kapil; Brady, Michael; Shapiro, Robert (2004) Selective abolition of pancreatic RNase binding to its inhibitor protein. Proc Natl Acad Sci U S A 101:53-8
|
|
Holloway, Daniel E; Chavali, Gayatri B; Hares, Michelle C et al. (2004) Crystallographic studies on structural features that determine the enzymatic specificity and potency of human angiogenin: Thr44, Thr80, and residues 38-41. Biochemistry 43:1230-41
|
|
Jenkins, Jeremy L; Kao, Richard Y T; Shapiro, Robert (2003) Virtual screening to enrich hit lists from high-throughput screening: a case study on small-molecule inhibitors of angiogenin. Proteins 50:81-93
|
|
Kumar, Kapil; Jenkins, Jeremy L; Jardine, Anwar M et al. (2003) Inhibition of mammalian ribonucleases by endogenous adenosine dinucleotides. Biochem Biophys Res Commun 300:81-6
|
|
Jenkins, Jeremy L; Shapiro, Robert (2003) Identification of small-molecule inhibitors of human angiogenin and characterization of their binding interactions guided by computational docking. Biochemistry 42:6674-87
|
|
Tonan, Kenji; Xu, Ping; Jenkins, Jeremy L et al. (2003) Unexpected binding mode for 2'-phosphoadenosine-based nucleotide inhibitors in complex with human angiogenin revealed by heteronuclear NMR spectroscopy. Biochemistry 42:11137-49
|
|
Teufel, Daniel P; Kao, Richard Y T; Acharya, K Ravi et al. (2003) Mutational analysis of the complex of human RNase inhibitor and human eosinophil-derived neurotoxin (RNase 2). Biochemistry 42:1451-9
|
|
Holloway, Daniel E; Shapiro, Robert; Hares, Michelle C et al. (2002) Guest-host crosstalk in an angiogenin-RNase A chimeric protein. Biochemistry 41:10482-9
|
|
Leonidas, Demetres D; Shapiro, Robert; Subbarao, Gowtham V et al. (2002) Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency. Biochemistry 41:2552-62
|
