Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA089640-19
Application #
6628469
Study Section
Pathology B Study Section (PTHB)
Program Officer
Spalholz, Barbara A
Project Start
2001-02-01
Project End
2006-01-31
Budget Start
2003-02-01
Budget End
2004-01-31
Support Year
19
Fiscal Year
2003
Total Cost
$226,575
Indirect Cost
Name
Thomas Jefferson University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
053284659
City
Philadelphia
State
PA
Country
United States
Zip Code
19107
La Rocca, Gaspare; Shi, Bin; Sepp-Lorenzino, Laura et al. (2011) Expression of micro-RNA-145 is regulated by a highly conserved genomic sequence 3' to the pre-miR. J Cell Physiol 226:602-7
La Rocca, Gaspare; Shi, Bin; Audia, Alessandra et al. (2011) Regulation of microRNA-145 by growth arrest and differentiation. Exp Cell Res 317:488-95
La Rocca, Gaspare; Badin, Margherita; Shi, Bin et al. (2009) Mechanism of growth inhibition by MicroRNA 145: the role of the IGF-I receptor signaling pathway. J Cell Physiol 220:485-91
Chen, Jia; Capozza, Franco; Wu, An et al. (2008) Regulation of insulin receptor substrate-1 expression levels by caveolin-1. J Cell Physiol 217:281-9
Wu, An; Chen, Jia; Baserga, Renato (2008) The role of insulin receptor substrate-1 in the oncogenicity of simian virus 40 T antigen. Cell Cycle 7:1999-2002
Sun, Hongzhi; Baserga, Renato (2008) The role of insulin receptor substrate-1 in transformation by v-src. J Cell Physiol 215:725-32
Shi, Bin; Sepp-Lorenzino, Laura; Prisco, Marco et al. (2007) Micro RNA 145 targets the insulin receptor substrate-1 and inhibits the growth of colon cancer cells. J Biol Chem 282:32582-90
Dalmizrak, Ozlem; Wu, An; Chen, Jia et al. (2007) Insulin receptor substrate-1 regulates the transformed phenotype of BT-20 human mammary cancer cells. Cancer Res 67:2124-30
Sun, Hongzhi; Tu, Xiao; Baserga, Renato (2006) A mechanism for cell size regulation by the insulin and insulin-like growth factor-I receptors. Cancer Res 66:11106-9
DeAngelis, T; Chen, J; Wu, A et al. (2006) Transformation by the simian virus 40 T antigen is regulated by IGF-I receptor and IRS-1 signaling. Oncogene 25:32-42

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