The overall goal of the proposed case-control study is to estimate the risk of specific childhood cancers associated with in utero exposure to pesticides (fungicides, herbicides and insecticides) used in agricultural settings, with particular emphasis on differential risk by race/ethnicity. In the process of addressing the study goal, we will be developing two tools which will have wider applications for public health research in Texas populations: 1) a geographic information system (GIS) capable of producing historical agricultural land use maps for a majority of Texas counties; and 2) a crop-specific Pesticide Exposure Index (PEI) for use in evaluating exposure to agricultural pesticides based on cropping and pesticide use patterns. These data applications will be of particular use in evaluating public health outcomes in rural populations.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA092670-02
Application #
6522809
Study Section
Special Emphasis Panel (ZRG1-SNEM-2 (02))
Program Officer
Erickson, Burdette (BUD) W
Project Start
2001-09-30
Project End
2006-08-31
Budget Start
2002-09-01
Budget End
2003-08-31
Support Year
2
Fiscal Year
2002
Total Cost
$196,425
Indirect Cost
Name
Texas A&M University
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
City
College Station
State
TX
Country
United States
Zip Code
77845
Marcotte, Erin L; Druley, Todd E; Johnson, Kimberly J et al. (2017) Parental Age and Risk of Infant Leukaemia: A Pooled Analysis. Paediatr Perinat Epidemiol 31:563-572
Von Behren, Julie; Spector, Logan G; Mueller, Beth A et al. (2011) Birth order and risk of childhood cancer: a pooled analysis from five US States. Int J Cancer 128:2709-16
Johnson, K J; Carozza, S E; Chow, E J et al. (2011) Birth characteristics and childhood carcinomas. Br J Cancer 105:1396-401
Chow, Eric J; Puumala, Susan E; Mueller, Beth A et al. (2010) Childhood cancer in relation to parental race and ethnicity: a 5-state pooled analysis. Cancer 116:3045-53
Johnson, Kimberly J; Carozza, Susan E; Chow, Eric J et al. (2009) Parental age and risk of childhood cancer: a pooled analysis. Epidemiology 20:475-83
Carozza, Susan E; Li, Bo; Wang, Qing et al. (2009) Agricultural pesticides and risk of childhood cancers. Int J Hyg Environ Health 212:186-95
Puumala, Susan E; Carozza, Susan E; Chow, Eric J et al. (2009) Childhood cancer among twins and higher order multiples. Cancer Epidemiol Biomarkers Prev 18:162-8
Spector, Logan G; Puumala, Susan E; Carozza, Susan E et al. (2009) Cancer risk among children with very low birth weights. Pediatrics 124:96-104
Walker, K M; Carozza, S; Cooper, S et al. (2007) Childhood cancer in Texas counties with moderate to intense agricultural activity. J Agric Saf Health 13:9-24