Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA095200-01S1
Application #
6759118
Study Section
Special Emphasis Panel (ZRG1)
Program Officer
Lees, Robert G
Project Start
2002-07-01
Project End
2005-06-30
Budget Start
2003-04-01
Budget End
2003-06-30
Support Year
1
Fiscal Year
2003
Total Cost
$22,184
Indirect Cost

  Institution

Name
University of Maryland Baltimore
Department
Pharmacology
Type
Schools of Pharmacy
DUNS #
188435911
City
Baltimore
State
MD
Country
United States
Zip Code
21201

  Publications

Chen, Fengming; Hancock, Chad N; Macias, Alba T et al. (2006) Characterization of ATP-independent ERK inhibitors identified through in silico analysis of the active ERK2 structure. Bioorg Med Chem Lett 16:6281-7
Hancock, Chad N; Macias, Alba; Lee, Eun Kyoung et al. (2005) Identification of novel extracellular signal-regulated kinase docking domain inhibitors. J Med Chem 48:4586-95
Boresch, Stefan; Leitgeb, Martin; Beselman, Aleksandra et al. (2005) Unexpected relative aqueous solubilities of a phosphotyrosine analogue and two phosphonate derivatives. J Am Chem Soc 127:4640-8
Macias, Alba T; Mia, Md Younus; Xia, Guanjun et al. (2005) Lead validation and SAR development via chemical similarity searching; application to compounds targeting the pY+3 site of the SH2 domain of p56lck. J Chem Inf Model 45:1759-66
Markowitz, Joseph; Chen, Ijen; Gitti, Rossi et al. (2004) Identification and characterization of small molecule inhibitors of the calcium-dependent S100B-p53 tumor suppressor interaction. J Med Chem 47:5085-93